Results 321 to 330 of about 3,524,198 (392)
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Pharmacokinetics of Antifungal Agents
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 1993The authors have evaluated the pharmacokinetics of four antifungal agents used in the therapy of fungal peritonitis. Amphotericin B (Amph B) poorly diffuses from blood into peritoneal fluid, which Intraperitoneal administration induces severe abdominal pain.
M V Pellanda +4 more
openaire +3 more sources
Hospital Medicine, 2004
With the relentless increase in invasive fungal infections, particularly in critically ill and immunocompromised patients, it is good to know that there are new additions to the antifungal armamentarium. These include not only new formulations of existing drugs and the development of new triazole agents, but also the introduction of a new class of ...
Anjali Shetty, Rosemary Ann Barnes
openaire +5 more sources
With the relentless increase in invasive fungal infections, particularly in critically ill and immunocompromised patients, it is good to know that there are new additions to the antifungal armamentarium. These include not only new formulations of existing drugs and the development of new triazole agents, but also the introduction of a new class of ...
Anjali Shetty, Rosemary Ann Barnes
openaire +5 more sources
Seminars in Respiratory Infections, 2002
Treatment of fungal infections is an area of increasing concern. This is because of the complexity of underlying illness in affected patients as well as the limited number of antifungal agents available for use. Current strategies focus on prevention of these infections in patients at high risk; however, this has the potential to lead to the emergence ...
John R. Perfect +2 more
openaire +6 more sources
Treatment of fungal infections is an area of increasing concern. This is because of the complexity of underlying illness in affected patients as well as the limited number of antifungal agents available for use. Current strategies focus on prevention of these infections in patients at high risk; however, this has the potential to lead to the emergence ...
John R. Perfect +2 more
openaire +6 more sources
Antifungal agents, WO2009025733
Expert Opinion on Therapeutic Patents, 2009The incidence and prevalence of serious mycoses continues to be a public health problem. These infections are an important cause of morbidity and mortality, especially in immunocompromised patients. The present patent deals with isolation and characterization of a 'pure' mixture of two novel isoxazolidinone-containing natural products from two new ...
Deshpande Sunita Ranjan +2 more
openaire +3 more sources
Plant-Derived Products as Antibacterial and Antifungal Agents in Human Health Care.
Current Medicinal Chemistry, 2019A number of papers reporting antimicrobial properties of extracts, essential oils, resins and various classes of compounds isolated from higher plants has been published in recent years; however, a comprehensive analysis of plant-derived antimicrobial ...
L. Kokoska +3 more
semanticscholar +1 more source
Bioorganic & Medicinal Chemistry Letters, 2003
Compounds based on sordaricin were prepared via organometallic addition onto a fully protected sordaricin aldehyde. The fungal growth inhibition profiles for these compounds were established and the results are presented here. The synthesis of homologated sordaricin as well as ether and ester derivatives is presented, and structural rearrangement ...
John F. Barrett +11 more
openaire +3 more sources
Compounds based on sordaricin were prepared via organometallic addition onto a fully protected sordaricin aldehyde. The fungal growth inhibition profiles for these compounds were established and the results are presented here. The synthesis of homologated sordaricin as well as ether and ester derivatives is presented, and structural rearrangement ...
John F. Barrett +11 more
openaire +3 more sources
Expert Opinion on Drug Metabolism & Toxicology, 2019
Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John +3 more
semanticscholar +1 more source
Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John +3 more
semanticscholar +1 more source
The Indian Journal of Pediatrics, 2004
Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment.
Walid Abuhammour, Eyassu Habte-Gaber
openaire +2 more sources
Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment.
Walid Abuhammour, Eyassu Habte-Gaber
openaire +2 more sources
Journal of Agricultural and Food Chemistry, 2018
Certain types of nanoparticles, especially zinc oxide nanoparticles (ZnONPs), are widely reported to be capable of the inhibition of harmful bacteria, yeasts, and filamentous fungi. The unique physicochemical and biological properties of ZnONPs also make
Qi Sun, Jianmei Li, T. Le
semanticscholar +1 more source
Certain types of nanoparticles, especially zinc oxide nanoparticles (ZnONPs), are widely reported to be capable of the inhibition of harmful bacteria, yeasts, and filamentous fungi. The unique physicochemical and biological properties of ZnONPs also make
Qi Sun, Jianmei Li, T. Le
semanticscholar +1 more source