A novel pan-fungal screening platform for antifungal drug discovery: proof of principle study. [PDF]
Antimicrob Agents ChemotherInman R, Warris A, Bignell E.
europepmc +1 more source
5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus [PDF]
, 2020 Billmyre, R. Blake +4 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Candidiasis: Insights into Virulence Factors, Complement Evasion and Antifungal Drug Resistance. [PDF]
MicroorganismsGaffar NR +2 more
europepmc +1 more source
Dysfunction of Prohibitin 2 Results in Reduced Susceptibility to Multiple Antifungal Drugs via Activation of the Oxidative Stress-Responsive Transcription Factor Pap1 in Fission Yeast [PDF]
, 2018 Qiannan Liu +8 more
openalex +1 more source
Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay
Drug Testing and Analysis, EarlyView.Hair analysis in children from a rural community in Paraguay reveals exposure to organophosphates, pyrethroids, neonicotinoids, fungicides, herbicides, and endocrine disruptors, highlighting the urgent need for stricter environmental protections and preventive health measures. ABSTRACT Chronic exposure to pesticides can cause carcinogenic, reproductive,
Stela Benitez Leite +5 more
wiley +1 more source
Structural insights into fungal and human topoisomerase II with implications for in silico antifungal drug design. [PDF]
Sci RepSappati S +3 more
europepmc +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen +6 more
wiley +1 more source
Impact of inter-species hybridisation on antifungal drug response in the Saccharomyces genus. [PDF]
BMC GenomicsVisinoni F +7 more
europepmc +1 more source
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Environmental Toxicology and Chemistry, EarlyView.Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz +4 more
wiley +1 more source