British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
Tissue Distribution after Intravenous Dosing of Micafungin, an Antifungal Drug, to Rats
, 2004 Toshiro Niwa +9 more
openalex +2 more sources
Comparsion ofin vitro activities of antifungal drugs and propolis against yeasts isolated from patients with superficial mycoses [PDF]
, 2007 Sibel Sílící +2 more
openalex +1 more source
Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series
British Journal of Clinical Pharmacology, EarlyView.Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen +6 more
wiley +1 more source
Deletion of ADA2 Increases Antifungal Drug Susceptibility and Virulence in Candida glabrata
Antimicrobial Agents and Chemotherapy, 2018 Shang-Jie Yu +2 more
semanticscholar +1 more source
Antifungal therapeutic drug monitoring: focus on drugs without a clear recommendation.
Clinical Microbiology and Infection, 2020 A. Gómez-López
semanticscholar +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
BMEMat, EarlyView.The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT The anatomy, histochemistry, and secondary metabolite composition were investigated on the drupes of Piper malgassicum, one of the components of the spice voatsiperifery pepper. The high amount of piperine recorded with high‐performance liquid chromatography with photodiode‐array detection analysis was localized with histochemistry mainly ...
Sara Falsini +11 more
wiley +1 more source
In Vitro Activities of Various Antifungal Drugs against Aspergillus terreus : Global Assessment Using the Methodology of the European Committee on Antimicrobial Susceptibility Testing [PDF]
, 2008 Cornelia Lass‐Flörl +4 more
openalex +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT Lupeol is a natural product commonly found in many vegetables and fruits in significant quantities. Previous studies have demonstrated the relevant activity of lupeol against various tumor cell lines, suggesting that the natural product could be a promising agent for cancer treatment.
Daniel Crístian Ferreira Soares +6 more
wiley +1 more source