Results 251 to 260 of about 197,518 (344)

A Review of Antifungal Peptides: Basis to New Era of Antifungal Drugs

, 2016
Yazan Akkam
openalex   +1 more source

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

Food Frontiers, EarlyView.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh, Raz Abdulqadir, Indira Kumari Verma, Yashika Awasthi, Arun Ratn, Juhi Sharma, Manmeet Rawat, Megh Singh Dhakad, Jasbir Dalal, Yash Gupta, Bhisham Narayan Singh, Divakar Sharma   +11 more
wiley   +1 more source

The Gcn5 lysine acetyltransferase mediates cell wall remodeling, antifungal drug resistance, and virulence of <i>Candida auris</i>. [PDF]

mSphere
Chauhan M, Shivarathri R, Aptekmann AA, Chowdhary A, Kuchler K, Desai JV, Chauhan N.   +6 more
europepmc   +1 more source

Rutaceae Zanthoxylum–Derived 7‐Demethylsuberosin Alleviates the Rheumatoid Arthritis Through Inhibiting the Maturation of Dendritic Cells via Targeting MAPK14 Functional Food‐Based 7‐Demethylsuberosin

Food Frontiers, EarlyView.
This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han, Bo Wang, Luyang Han, Yanbo Zhu, Jiawei Dong, Yuekang Xu, Xiaoying Liu, Jinyao Li   +7 more
wiley   +1 more source

Insights into the role of sterol metabolism in antifungal drug resistance: a mini-review. [PDF]

Front Microbiol
Tanwar S, Kalra S, Bari VK.
europepmc   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

The prevalence, patterns, and antifungal drug resistance of bloodstream infection-causing fungi in Sichuan Province, China (2019-2023): a retrospective observational study using national monitoring data. [PDF]

Front Microbiol
Deng J, Liu Y, Shu L, Zhou D, Xie Y, Ma Y, Kang M.   +6 more
europepmc   +1 more source

Additional file 4 of In vitro combination effects and mechanisms of Revaprazan with Triazole antifungal drugs on Aspergillus

Cheng, Wenxu, Shen, Min, Wan, Lijia, Chen, Tian, Wang, Lingxi, Zhang, Heng, Sun, Yi   +6 more
openalex   +1 more source

Comparative Analysis of Isavuconazole DDIs With Other Azole Antifungal Drugs and PBPK Model‐Informed Dosing Recommendations for Anticancer Drugs [PDF]

Theunis C. Goosen, Xiaofeng Wu, Jian Lin, N. Cheruvu, Susan Raber, María Henriqueta Figueiredo, Manthena V. S. Varma   +6 more
openalex   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source