Results 31 to 40 of about 4,025,807 (397)

New strategic insights into managing fungal biofilms [PDF]

open access: yes, 2015
Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa   +6 more
core   +10 more sources

Overproduction of gentamicin B in industrial strain Micromonospora echinospora CCTCC M 2018898 by cloning of the missing genes genR and genS

open access: yesMetabolic Engineering Communications, 2019
In pharmaceutical industry, isepamicin is mainly manufactured from gentamicin B, which is produced by Micromonospora echinospora as a minor component of the gentamicin complex.
Yingying Chang   +8 more
doaj   +1 more source

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

open access: yes, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose   +7 more
core   +1 more source

In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis [PDF]

open access: yes, 2017
Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms.
Bougnoux, Marie Élisabeth   +5 more
core   +1 more source

Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]

open access: yes, 2010
Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Nandkumar M. Kamat   +1 more
core   +2 more sources

The Future of Antifungal Drug Therapy: Novel Compounds and Targets

open access: yesAntimicrobial Agents and Chemotherapy, 2020
Fungal infections are a universal problem and are routinely associated with high morbidity and mortality rates in immunocompromised patients. Existing therapies comprise five different classes of antifungal agents, four of which target the synthesis of ...
C. M. Fernandes   +6 more
semanticscholar   +1 more source

High Efficiency Drug Repurposing Design for New Antifungal Agents

open access: yesMethods and Protocols, 2019
Current antifungal interventions have often limited efficiency in treating fungal pathogens, particularly those resistant to commercial drugs or fungicides.
Jong H. Kim   +6 more
doaj   +1 more source

Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]

open access: yes, 2008
Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian   +2 more
core   +1 more source

Utilization Trends of Antiviral and Antifungal Agents for Human Systemic Use in Tanzania From 2010 to 2017 Using the World Health Organization Collaborating Centre for Drug Statistics Methodology

open access: yesFrontiers in Tropical Diseases, 2021
Introduction The increase in antimicrobial consumption contributes to the emergence of antimicrobial resistance (AMR). Many studies have investigated the patterns of antibacterial consumption and antibacterial resistance.
Hafidh Hamim   +8 more
semanticscholar   +1 more source

A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Surgery, 2021
Objectives/Hypothesis: To perform a systematic review and meta-analysis to compare the efficacy of and complications associated with antifungal drugs and traditional antiseptic medication for the treatment of otomycosis.Data Sources: The PubMed, EMBASE ...
Shunyu Wu   +3 more
doaj   +1 more source

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