Special Issue: Novel Antifungal Drug Discovery
Journal of Fungi, 2016 This Special Issue is designed to highlight the latest research and development on new antifungal compounds with mechanisms of action different from the ones of polyenes, azoles, and echinocandins.
Maurizio Del Poeta
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Comparative Characterization of G Protein α Subunits in Aspergillus fumigatus
Pathogens, 2020 Trimeric G proteins play a central role in the G protein signaling in filamentous fungi and Gα subunits are the major component of trimeric G proteins. In this study, we characterize three Gα subunits in the human pathogen Aspergillus fumigatus.
Yong-Ho Choi +4 more
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Emerging Polymer-Based Nanosystem Strategies in the Delivery of Antifungal Drugs
Pharmaceutics, 2023 Nanosystems-based antifungal agents have emerged as an effective strategy to address issues related to drug resistance, drug release, and toxicity. Among the diverse materials employed for antifungal drug delivery, polymers, including polysaccharides ...
Yuan Xin +3 more
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Synthesis, characterization and antifungal assessment of optically active bis-organotin compounds derived from (S)-BINOL diesters [PDF]
, 2019 Background: Organotin(IV) derivatives have appeared recently as potential biologically active metallopharmaceuticals exhibiting a variety of therapeutic activities.
Costantino, Andrea Rosana +6 more
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Antifungal Mechanism of Action of Lauryl Betaine Against Skin-Associated Fungus Malassezia restricta
Mycobiology, 2019 Betaine derivatives are considered major ingredients of shampoos and are commonly used as antistatic and viscosity-increasing agents. Several studies have also suggested that betaine derivatives can be used as antimicrobial agents.
Eunsoo Do +9 more
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Memorias do Instituto Oswaldo Cruz, 2004 One of the main opportunistic fungal infections amongst immunocompromised individuals is oral candidosis, which has been found in up to 90% of human immunodeficiency virus (HIV)-infected patients.
NR Melo +7 more
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Development and research progress of anti-drug resistant fungal drugs
Journal of Infection and Public Health, 2022 With the widespread use of immunosuppressive agents and the increase in patients with severe infections, the incidence of fungal infections worldwide has increased year by year.
Xiangyi Cui +3 more
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Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]
, 2017 This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba +3 more
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ASDCD: antifungal synergistic drug combination database. [PDF]
PLoS ONE, 2014 Finding effective drugs to treat fungal infections has important clinical significance based on high mortality rates, especially in an immunodeficient population.
Xing Chen +7 more
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Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]
, 2016 Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
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