Combination of Posaconazole and Amphotericin B in the Treatment of Candida glabrata Biofilms
Microorganisms, 2018 Candidemia cases have been increasing, especially among immunosuppressed patients. Candida glabrata is one of the most resistant Candida species, especially to the azole drugs, resulting in a high demand for therapeutic alternatives.
Célia F. Rodrigues +2 more
doaj +1 more source
Solid lipid nanoparticles, an effective carrier for classical antifungal drugs
Saudi Pharmaceutical Journal, 2023 Solid-lipid nanoparticles (SLNs) are an innovative group of nanosystems used to deliver medicine to their respective targets with better efficiency and bioavailability in contrast to classical formulations.
Saud Almawash
doaj +1 more source
Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]
, 2019 Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina +3 more
core
Antimicrobial Activities and Mechanisms of Magnesium Oxide Nanoparticles (nMgO) against Pathogenic Bacteria, Yeasts, and Biofilms. [PDF]
, 2018 Magnesium oxide nanoparticle (nMgO) is a light metal based antimicrobial nanoparticle that can be metabolized and fully resorbed in the body. To take advantage of the antimicrobial properties of nMgO for medical use, it is necessary to determine the ...
Grelling, Nathaniel +4 more
core +3 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroductionThe increasing resistance of Candida albicans (C. albicans) to conventional antifungal drugs poses a great challenge to the clinical treatment of infections caused by this yeast.
Xiuyun Li +5 more
doaj +1 more source
Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]
, 2016 Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Discovery of a Novel Antifungal Agent in the Pathogen Box
mSphere, 2017 Human fungal pathogens cause over 2 million infections per year and are major drivers of morbidity and mortality. Cryptococcus neoformans and Candida albicans are two of the most common fungal pathogens of humans, together accounting for a staggering 1.4
François L. Mayer, James W. Kronstad
doaj +1 more source
Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study [PDF]
, 2013 Peer reviewedPublisher ...
Gow, Neil A R +8 more
core +4 more sources