Results 101 to 110 of about 85,603 (246)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Patient‐Derived 3D‐Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy

Advanced Science, EarlyView.
Leveraging 3D bioprinting, this study establishes patient‐derived in vitro models of intrahepatic cholangiocarcinoma. These models faithfully recapitulate the histopathology, molecular profiles, and genomic characteristics of the original patient tumors.
Yuce Lu, Liwei Du, Minghao Sun, Kai Zhang, Mingchang Pang, Shangze Jiang, Jiaxun Dong, Xiyue Liu, Bao Jin, Fu Xu, Hang Sun, Jiangang Zhang, Huiyu Yang, Xiaobo Yang, Xin Lu, Yiyao Xu, Haitao Zhao, Shunda Du, Xinting Sang, Yongchang Zheng, Lei Zhang, Xueshuai Wan, Huayu Yang, Yilei Mao   +23 more
wiley   +1 more source

Current Landscape: Use of Supercritical CO2 in the Wood Industry

Advanced Energy and Sustainability Research, EarlyView.
The application of supercritical carbon dioxide (scCO2) to successfully dewater as well as extract resin from wood is becoming increasingly popular due to its greener and less energy‐intensive approach. With world focus shifting to developing methods with greater efficiency while decreasing harm to the environment, scCO2 applications have begun to set ...
Anthony Dahdah, Subashani Maniam
wiley   +1 more source

Cellpose+, a Morphological Analysis Tool for Feature Extraction of Stained Cell Images

Advanced Intelligent Discovery, EarlyView.
We introduce Cellpose plus, a morphological and geometrical analysis tool for feature extraction of stained cell images built over Cellpose, a state‐of‐the‐art cell segmentation framework. We also introduce a dataset of DAPI and FITC stained cells to which our new method is applied.
Israel A. Huaman, Fares D. E. Ghorabe, Sofya S. Chumakova, Alexandra A. Pisarenko, Alexey E. Dudaev, Tatiana G. Volova, Galina A. Ryltseva, Sviatlana A. Ulasevich, Ekaterina I. Shishatskaya, Ekaterina V. Skorb, Pavel S. Zun   +10 more
wiley   +1 more source

Emerging Applications of Triazole Antifungal Drugs. [PDF]

Int J Mol Sci
Soldi LR, Oliveira APL, Silva MJB.
europepmc   +1 more source

Emerging Polymer-Based Nanosystem Strategies in the Delivery of Antifungal Drugs. [PDF]

Pharmaceutics, 2023
Xin Y, Quan L, Zhang H, Ao Q.
europepmc   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Aloe vera–Based Green Synthesis of Silver Nanoparticles With Characterization, Potent Antibacterial and Antioxidant Properties

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Green synthesis has emerged as a suitable alternative to the traditional method for manufacturing nanoparticles (NPs) as it provides a safer, sustainable, healthy, and environmental path for the NPs synthesis. Silver nanoparticles (AgNPs) were prepared using a green method with locally sourced Aloe vera leaf extract.
Janaki Baral, Sushant Timalsina, Sujan Dhungana, Laxmi Tiwari, Devendra Khadka, Bhoj Raj Poudel   +5 more
wiley   +1 more source

In vitro combination effects and mechanisms of Revaprazan with Triazole antifungal drugs on Aspergillus. [PDF]

BMC Microbiol
Cheng W, Shen M, Wan L, Chen T, Wang L, Zhang H, Sun Y.   +6 more
europepmc   +1 more source

Recent Progress in Research on Mitochondrion-Targeted Antifungal Drugs: a Review. [PDF]

Antimicrob Agents Chemother, 2023
Qin Y, Wang J, Lv Q, Han B.
europepmc   +1 more source