A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug +2 more
wiley +1 more source
In Vitro Evaluation of 5-Fluorouridine as an Adjuvant to Antifungal Drugs and Molecular Insights into Resistance to This Compound in <i>Candida</i> Species. [PDF]
Janeczko M, Lenarczyk E.
europepmc +1 more source
Pythium insidiosum: insights into biofilm formation and antibiofilm activity of antifungal drugs. [PDF]
Pippi B +10 more
europepmc +1 more source
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source
Evaluation of the readability level of the package inserts of topical antifungal drugs. [PDF]
Uysal E.
europepmc +1 more source
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Next-generation antifungal drugs: Mechanisms, efficacy, and clinical prospects. [PDF]
Lu X +9 more
europepmc +1 more source
Role of paracoccin on Paracoccidioides brasiliensis virulence and susceptibility to antifungal drugs in the Galleria mellonella larvae model. [PDF]
de Souza Pitangui N +4 more
europepmc +1 more source
Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande +6 more
wiley +1 more source

