Results 171 to 180 of about 92,209 (296)

A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling

open access: yesChemistry – A European Journal, EarlyView.
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug   +2 more
wiley   +1 more source

Pythium insidiosum: insights into biofilm formation and antibiofilm activity of antifungal drugs. [PDF]

open access: yesBraz J Microbiol, 2023
Pippi B   +10 more
europepmc   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

open access: yesChemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

open access: yesChemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami   +2 more
wiley   +1 more source

Next-generation antifungal drugs: Mechanisms, efficacy, and clinical prospects. [PDF]

open access: yesActa Pharm Sin B
Lu X   +9 more
europepmc   +1 more source

Role of paracoccin on Paracoccidioides brasiliensis virulence and susceptibility to antifungal drugs in the Galleria mellonella larvae model. [PDF]

open access: yesVirulence, 2023
de Souza Pitangui N   +4 more
europepmc   +1 more source

Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals

open access: yesChemistry – A European Journal, EarlyView.
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande   +6 more
wiley   +1 more source

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