Results 31 to 40 of about 502,199 (230)

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity [PDF]

, 2014
SummaryRecognition of fungal pathogens by C-type lectin receptor (CLR) dectin-1 on human dendritic cells is essential for triggering protective antifungal TH1 and TH17 immune responses.
Geijtenbeek, Teunis B.H., Kaptein, Tanja M., Wevers, Brigitte A., Zijlstra-Willems, Esther M., Gringhuis, Sonja I., Geijtenbeek, Teunis B. H., Theelen, Bart, Boekhout, Teun   +7 more
core   +1 more source

Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis

Frontiers in Microbiology, 2015
Invasive aspergillosis (IA) is a life-threatening fungal disease commonly diagnosed among individuals with immunological deficits, namely hematological patients undergoing chemotherapy or allogeneic hematopoietic stem cell transplantation.
Ana eOliveira-Coelho, Ana eOliveira-Coelho, Fernando eRodrigues, Fernando eRodrigues, António eCampos, João F. Lacerda, João F. Lacerda, Agostinho eCarvalho, Agostinho eCarvalho, Cristina eCunha, Cristina eCunha   +10 more
doaj   +1 more source

A gut-oral microbiome–driven axis controls oropharyngeal candidiasis through retinoic acid

JCI Insight, 2022
A side effect of antibiotics is outgrowth of the opportunistic fungus Candida albicans in the oropharynx (oropharyngeal candidiasis, OPC). IL-17 signaling is vital for immunity to OPC, but how the microbiome impacts antifungal immunity is not well ...
Felix E.Y. Aggor, Martinna Bertolini, Chunsheng Zhou, Tiffany C. Taylor, Darryl A. Abbott, Javonn Musgrove, Vincent M. Bruno, Timothy W. Hand, Sarah L. Gaffen   +8 more
doaj   +1 more source

Dendritic Cells in Antifungal Immunity and Vaccine Design [PDF]

, 2012
Life-threatening fungal infections have increased in recent years while treatment options remain limited. The development of vaccines against fungal pathogens represents a key advance sorely needed to combat the increasing fungal disease threat ...
Roy, René M., Klein, Bruce S.
core   +1 more source

Exploring how antibiotics impair antifungal immunity [PDF]

Prolonged antibiotic use is a controllable risk factor for systemic candidiasis. In recent years, antibiotics have been shown to have off-target detrimental effects on immune cells, but whether antibiotics disrupt antifungal immunity is unknown. Drummond
Bojang, Ebrima
core   +5 more sources

Neuro-Immune Mechanisms of Anti-Cryptococcal Protection

Journal of Fungi, 2017
Cryptococcal meningitis (CM) is a life-threatening fungal disease affecting both immunosuppressed and immunocompetent people. The main causative agent of CM is Cryptococcus neoformans, a basidiomycete fungus prevalent in the environment.
Rebecca A. Drummond
doaj   +1 more source

Use of volatile fingerprints for rapid screening of antifungal agents for efficacy against dermatophyte Trichophyton species [PDF]

, 2010
The potential of using an electronic nose (E-nose) as a rapid technique for screening the responses of dermatophytes to antifungal agents was studied.
Adriaans, B, Barr, Hugh, Magan, Naresh, Sahgal, N, Sahgal, Natasha, Barr, H, Magan, N, Naraghi, Kamran, Adriaans, Beverley, Naraghi, K   +9 more
core   +1 more source

Fungal biofilm resistance [PDF]

, 2012
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon, Williams, Craig, Rajendran, Ranjith, Ranjith Rajendran, Gordon Ramage, Leighann Sherry, Sherry, Leighann, Craig Williams   +7 more
core   +1 more source

Mucosal IgA Prevents Commensal Candida albicans Dysbiosis in the Oral Cavity

Frontiers in Immunology, 2020
The fungus Candida albicans colonizes the oral mucosal surface of 30–70% of healthy individuals. Due to local or systemic immunosuppression, this commensal fungus is able to proliferate resulting in oral disease, called oropharyngeal candidiasis (OPC ...
Nicolas Millet, Nicolas Millet, Norma V. Solis, Norma V. Solis, Marc Swidergall, Marc Swidergall, Marc Swidergall   +6 more
doaj   +1 more source

Peptidoglycan Recognition Proteins (PGRPs) Modulates Mosquito Resistance to Fungal Entomopathogens in a Fungal-Strain Specific Manner

Frontiers in Cellular and Infection Microbiology, 2020
Fungal entomopathogens are potential tools for the control of mosquito vectors that transmit infectious agents that cause disease in humans and animals.
José L. Ramirez, Ephantus J. Muturi, Lina B. Flor-Weiler, Karl Vermillion, Alejandro P. Rooney   +4 more
doaj   +1 more source