Results 11 to 20 of about 502,199 (230)

Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity

Frontiers in Immunology, 2018
Of all the pathogen recognition receptor families, C-type lectin receptor (CLR)-induced intracellular signal cascades are indispensable for the initiation and regulation of antifungal immunity.
Wallace Langdon, Guoxin Lin
exaly   +4 more sources

Antifungal Th Immunity: Growing up in Family [PDF]

Frontiers in Immunology, 2014
Fungal diseases represent an important paradigm in immunology since they can result from either the lack of recognition or over–activation of the inflammatory response.
Luigina Romani, Mónica Borghi, Vasileios Oikonomou   +2 more
exaly   +4 more sources

MYO1F regulates antifungal immunity by regulating acetylation of microtubules [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2021
Cun-Jin Zhang, Chenhui Wang, Xiaoxia Li   +2 more
exaly   +2 more sources

Symbiont-Induced HSP83 Establishes Two-Tiered Control of Antifungal Immunity in an Invasive Beetle-Fungus Complex. [PDF]

Adv Sci (Weinh)
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Yang Q, Liu Z, Yin Y, Su J, Yu D, Xing L, Zou Z, Kang L, Sun J.   +8 more
europepmc   +2 more sources

Intestinal fungi and antifungal secretory immunoglobulin A in Crohn’s disease

Frontiers in Immunology, 2023
The human gastrointestinal tract harbors trillions of commensal microorganisms. Emerging evidence points to a possible link between intestinal fungal dysbiosis and antifungal mucosal immunity in inflammatory bowel disease, especially in Crohn’s disease ...
Meng Sun, Jingyi Ju, Hongzhen Xu, Yufang Wang   +3 more
doaj   +1 more source

Disrupting the Dok3–Card9 Interaction with Synthetic Peptides Enhances Antifungal Effector Functions of Human Neutrophils

Pharmaceutics, 2023
Invasive fungal disease is an emerging and serious public health threat globally. The expanding population of susceptible individuals, together with the rapid emergence of multidrug-resistant fungi pathogens, call for the development of novel therapeutic
Jia Tong Loh, Joey Kay Hui Teo, Srinivasaraghavan Kannan, Chandra S. Verma, Hong-Hwa Lim, Kong-Peng Lam   +5 more
doaj   +1 more source

T cell responses to control fungal infection in an immunological memory lens

Frontiers in Immunology, 2022
In recent years, fungal vaccine research emanated significant findings in the field of antifungal T-cell immunity. The generation of effector T cells is essential to combat many mucosal and systemic fungal infections. The development of antifungal memory
Jaishree Sharma, Srinivasu Mudalagiriyappa, Som Gowda Nanjappa   +2 more
doaj   +1 more source

A Fun-Guide to Innate Immune Responses to Fungal Infections

Journal of Fungi, 2022
Immunocompromised individuals are at high risk of developing severe fungal infections with high mortality rates, while fungal pathogens pose little risk to most healthy people.
Thomas B. Burgess, Alison M. Condliffe, Philip M. Elks   +2 more
doaj   +1 more source

T Cell Antifungal Immunity and the Role of C-Type Lectin Receptors

Trends in Immunology, 2020
Fabian Salazar, Ivy Dambuza, Gordon Brown   +2 more
exaly   +2 more sources

Skin Immunity to Dermatophytes: From Experimental Infection Models to Human Disease

Frontiers in Immunology, 2020
Dermatophytoses (ringworms) are among the most frequent skin infections and are a highly prevalent cause of human disease worldwide. Despite the incidence of these superficial mycoses in healthy people and the compelling evidence on chronic and deep ...
Verónica L. Burstein, Verónica L. Burstein, Ignacio Beccacece, Ignacio Beccacece, Lorena Guasconi, Lorena Guasconi, Cristian J. Mena, Cristian J. Mena, Laura Cervi, Laura Cervi, Laura S. Chiapello, Laura S. Chiapello   +11 more
doaj   +1 more source