Case Report: Invasive fungal infection after anti-CD19 CAR-T cell therapy. Implication for antifungal prophylaxis [PDF]
CAR-T therapy has revolutionized the treatment of relapsed/refractory B-cell malignancies. Patients who are receiving such therapy are susceptible to an increased incidence of infections due to post-treatment immunosuppression.
Elsa Pennese +12 more
doaj +4 more sources
Antifungal prophylaxis in stem cell transplantation centers in Turkey [PDF]
OBJECTIVE: This study aimed to determine the current state of antifungal prophylaxis in Turkish stem cell transplantation (SCT) centers. METHODS: he were 38 active stem cell transplantation centers in Turkey, 28 of which were registered with the European
Hamdi Akan
doaj +4 more sources
Invasive Aspergillosis among Lung Transplant Recipients during Time Periods with Universal and Targeted Antifungal Prophylaxis—A Nationwide Cohort Study [PDF]
The optimal prevention strategy for invasive aspergillosis (IA) in lung transplant recipients (LTXr) is unknown. In 2016, the Danish guidelines were changed from universal to targeted IA prophylaxis. Previously, we found higher rates of adverse events in
Cornelia Geisler Crone +7 more
doaj +2 more sources
Cost-Effectiveness of Serum Galactomannan Surveillance during Mould-Active Antifungal Prophylaxis [PDF]
Serial galactomannan (GM) monitoring can aid the diagnosis of invasive aspergillosis (IA) and optimise treatment decisions. However, widespread adoption of mould-active prophylaxis has reduced the incidence of IA and challenged its use.
Ai Leng Khoo +8 more
doaj +2 more sources
Prophylaxis of Antifungal Drugs against Systemic Fungemia induced by Oral Candidiasis in Mice [PDF]
Oral mucositis is highly prevalent among the elderly, for whom oral care is often difficult. Oral mucositis, such as candidiasis, can induce systemic fungemia.
Kazunori Ninomiya +6 more
doaj +2 more sources
Mold-Active Antifungal Prophylaxis in Pediatric Patients with Cancer or Undergoing Hematopoietic Cell Transplantation [PDF]
Invasive fungal diseases (IFDs), in particular invasive mold infections, still pose considerable problems in the care of children and adolescents treated for cancer or undergoing hematopoietic cell transplantation.
Thomas Lehrnbecher +2 more
doaj +2 more sources
ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS [PDF]
Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the ...
Lourdes Vazquez
doaj +3 more sources
Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation [PDF]
Background Pediatric patients undergoing hematopoietic stem cell transplantation (HSCT) are at high risk of acquiring fungal infections. Antifungal prophylaxis shortly after transplantation is therefore indicated, but data for pediatric patients under 12
Döring Michaela +8 more
doaj +2 more sources
Diagnosis and Antifungal Prophylaxis for COVID-19 Associated Pulmonary Aspergillosis [PDF]
The COVID-19 pandemic has redemonstrated the importance of the fungal-after-viral phenomenon, and the question of whether prophylaxis should be used to prevent COVID-19-associated pulmonary aspergillosis (CAPA).
Armani M. Hawes, Nitipong Permpalung
doaj +2 more sources
Effectiveness of high efficiency particulate (HEPA) air condition combined with the antifungal prophylaxis on incidence, morbidity and mortality of invasive fungal infections in patients with acute myeloid leukemia: a retrospective single-center study [PDF]
IntroductionOur monocentric and retrospective study aimed to investigate the clinical effectivity of HEPA filters in combination with the antifungal drug prophylaxis in patients with AML undergoing intensive chemotherapy and allogeneic stem cell ...
Linda Preyer +14 more
doaj +2 more sources

