Results 301 to 310 of about 3,376,929 (374)

Emergence of multidrug-resistant <i>Candidozyma auris</i> in southern China: a multicenter study on genetic diversity and antifungal resistance. [PDF]

Front Microbiol
Guo P, Fang J, Wang R, Lin W, Jiang Y, Long J, Chen L, Huang X, Liao K, Peng Y.   +9 more
europepmc   +1 more source

Candida Bloodstream Infections: Comparison of Species Distributions and Antifungal Resistance Patterns in Community-Onset and Nosocomial Isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009

, 2010
Michael A. Pfaller, Gary J. Moet, S. A. Messer, Ronald N. Jones, Mariana Castanheira   +4 more
openalex   +2 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Disruption of the ATP-dependent unfoldase ClpX reverses antifungal resistance in Cryptococcus neoformans. [PDF]

Nat Commun
Woods M, Bermas A, Ball B, Muselius B, Chan N, Gutierrez-Gongora D, Ramezanpour S, McAlister JA, Sieber SA, Geddes-McAlister J.   +9 more
europepmc   +1 more source

Monitoring on Antifungal Resistance from Clinical Candida Species by E-Test

, 2008
Parisa Badiee, Abdolvahab Alborzi, Elaheh Shakiba, A. Joponi   +3 more
openalex   +1 more source

Senescent Mesenchymal Stromal Cells Differentially Alter Adipogenesis in Adipose Tissue, Skeletal Muscle, and Bone Marrow

Obesity, EarlyView.
ABSTRACT Objective Aging alters mesenchymal stromal cell (MSC) function, leading to dysregulated adipogenesis across tissues through biased lineage commitment. Fat redistribution from adipose depots to skeletal muscle and bone marrow is common in aging, but the underlying mechanisms remain unclear.
Xu Zhang, Madison L. Doolittle, Ting Fan, Utkarsh Tripathi, Yan Er Ng, Xinyi Jiang, João F. Passos, Diana Jurk, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Paul D. Robbins, Sundeep Khosla, Nathan K. LeBrasseur   +13 more
wiley   +1 more source

Candida auris infections in ICU patients: risk factors, outcomes, and antifungal resistance patterns. [PDF]

Crit Care
Choudhury S, Majhi K, Jena P, Mohanty S, Narayan YN, Paramita Jena P, Mishra SB, Panda S.   +7 more
europepmc   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

First Report of <i>Candida auris</i> Candidemia in Portugal: Genomic Characterisation and Antifungal Resistance-Associated Genes Analysis. [PDF]

J Fungi (Basel)
Miranda IM, Gonçalves MFM, Pinheiro D, Hilário S, Paiva JA, Guimarães JT, de Oliveira SC.   +6 more
europepmc   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source