Results 41 to 50 of about 55,690 (283)

A Prospective Surveillance Study of Candidaemia : Epidemiology, Risk Factors, Antifungal Treatment and Outcome in Hospitalized Patients [PDF]

, 2016
Funding This work was supported by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/Z. Data collection was supported by a grant from Pfizer.
Deshpande, Ashutosh, Hanson, Mary F., Johnson, Elizabeth M., Jones, Brian L., Munro, Carol A., Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Williams, Craig   +8 more
core   +2 more sources

Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris [PDF]

, 2019
The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Kean, Ryan, Ramage, Gordon
core   +2 more sources

Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets [PDF]

, 2014
BACKGROUND: Genome-wide microarrays have been useful for predicting chemical-genetic interactions at the gene level. However, interpreting genome-wide microarray results can be overwhelming due to the vast output of gene expression data combined with off-
Christadore, Lisa M., Kolaczyk, Eric D., Pham, Lisa, Schaus, Scott E.   +3 more
core   +1 more source

In vitro Antifungal Susceptibility of Agents for Superficial Phaeohyphomycosis

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2020
The selection of fungal isolates resistant to available therapy associated with an increase in the number of immunosuppressed patients has contributed to the incidence of infections caused by dematiaceous fungi. Thus, this study evaluated the therapeutic
Viviane Pagnussat, Gabriella da Rosa Monte Machado, Janaína Scarton, Alexandre Meneghello Fuentefria   +3 more
doaj   +1 more source

Recent trends in molecular diagnostics of yeast infections : from PCR to NGS [PDF]

, 2019
The incidence of opportunistic yeast infections in humans has been increasing over recent years. These infections are difficult to treat and diagnose, in part due to the large number and broad diversity of species that can underlie the infection.
Arastehfar, A, Boekhout, T, Buda De Cesare, G, Butler, G, Dolk, E, Gabaldón, Tony, Hafez, A, Hagen, F, Hovhannisyan, H, Hube, B, Iracane, E, Kostrzewa, M, Lackner, M, Lass-Flörl, C, Llorens, C, Mixão, V, Munro, C, Oliveira-Pacheco, J, OPATHY Consortium, the, Pekmezovic, M, Pérez-Hansen, A, Rodriguez Sánchez, Antonio, Sauer, FM, Sparbier, K, Stavrou, AA, Vaneechoutte, Mario, Vatanshenassan, M   +26 more
core   +2 more sources

Candidemia due to Candida lambica in a neutropenic oncology patient: A rare case report

Medical Mycology Case Reports
We report a rare case of Candida lambica candidemia in a 56-year-old male with acute myeloid leukemia undergoing intensive chemotherapy. Despite fluconazole prophylaxis, the patient developed persistent febrile neutropenia.
Sanam Nami, Mortaza Raeisi, Zahra Ramezanalipour, Parviz Hassanpour   +3 more
doaj   +1 more source

Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals. [PDF]

, 2018
Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease.
Bays, Derek, Dinh, Bao-Tran N, McHardy, Ian H, Pappagianis, Demosthenes, Stewart, Ethan, Thompson, George R, Waldman, Sarah   +6 more
core  

Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]

, 2017
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani, Nabil El Brahmi, Saïd El Kazzouli, Regis Laurent, Sonia Ladeira, Anne-Marie Caminade, Elzbieta Pedziwiatr-Werbicka, Eligia M. Szewcyk, Maria Bryszewska, Mosto M. Bousmina, Thierry Cresteil, Jean Pierre Majoral   +11 more
core   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies [PDF]

, 2015
Date of Acceptance: 23/07/2015 We thank Gillian Milne for help with electron microscopy, Sophie M. Schäfer for pilot experiments, and Emilia Mellado for strains. All authors acknowledge financial support of Gilead Sciences through Ph.D.
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Walker, Louise A   +3 more
core   +1 more source