Results 51 to 60 of about 44,945 (292)

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Candida antifungal drug resistance in sub-Saharan African populations: A systematic review [version 2; referees: 2 approved]

F1000Research, 2017
Background: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV co-infection.
Charlene Wilma Joyce Africa, Pedro Miguel dos Santos Abrantes   +1 more
doaj   +1 more source

Antifungal drug susceptibility of Candida albicans

East African Medical Journal, 2002
To determine the susceptibility of clinical isolates of Candida albicans and to establish the minimum inhibitory concentrations (MIC) to commonly used antifungal drugs.Laboratory based experiment.Mbagathi District Hospital, Nairobi, Kenya.Candida albicans isolated between 1998 and 2000 from the sputa of HIV/AIDS patients and throat swabs of children ...
L. W. Githinji, T. T. Ouko, Evans Amukoye, C. C. Bii   +3 more
openaire   +4 more sources

A Supramolecular Material for Controlling Kiwifruit Bacterial Canker

Advanced Science, EarlyView.
The matrine‐5‐methylsalicylic acid salt (MOS) is reported for its excellent antibacterial activity against Pseudomonas syringae pv. actinidiae (Psa), with advanced cell membrane penetration ability and strong affinities for potential targets. Furthermore, a nanosupramolecular delivery system MOS@hydroxypropyl‐beta‐cyclodextrin (HPCD) with improved ...
Xile Deng, Qiang Bian, Mingqing Zhou, Le Xie, Jichuan Zhang, Tianqi Liu, Yizhuo Zhang, Li Zhang, Jiaheng Zhang, Lianyang Bai   +9 more
wiley   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Investigating Antifungal Susceptibility in Candida Species With MALDI-TOF MS-Based Assays

Frontiers in Cellular and Infection Microbiology, 2019
Half of invasive fungal infections lead to death. Amongst pathogenic fungi, the most widespread species belong to the Candida genus and vary in their susceptibility to antifungal drugs.
Margot Delavy, Andrea R. Dos Santos, Clara M. Heiman, Alix T. Coste   +3 more
doaj   +1 more source

How Yeast Antifungal Resistance Gene Analysis Is Essential to Validate Antifungal Susceptibility Testing Systems

Frontiers in Cellular and Infection Microbiology, 2022
ObjectivesThe antifungal susceptibility testing (AFST) of yeast pathogen alerts clinicians about the potential emergence of resistance. In this study, we compared two commercial microdilution AFST methods: Sensititre YeastOne read visually (YO) and ...
Nicolas Pellaton, Dominique Sanglard, Frederic Lamoth, Frederic Lamoth, Alix T. Coste   +4 more
doaj   +1 more source

Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy

Advanced Science, EarlyView.
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley   +1 more source

Species distribution and in vitro antifungal susceptibility of oral yeast isolates from Tanzanian HIV-infected patients with primary and recurrent oropharyngeal candidiasis

BMC Microbiology, 2008
Background In Tanzania, little is known on the species distribution and antifungal susceptibility profiles of yeast isolates from HIV-infected patients with primary and recurrent oropharyngeal candidiasis. Methods A total of 296 clinical oral yeasts were
Rijs Antonius JMM, Helderman Wim, Mikx Frans HM, Mugusi Ferdinand, Simon Elison NM, Moshi Mainen J, Matee Mecky IN, Hamza Omar JM, van der Ven André JAM, Verweij Paul E   +9 more
doaj   +1 more source

A study of Candida albicans and non-albicans Candida species isolated from various clinical samples and their antifungal susceptibility pattern

Journal of Medical and Scientific Research, 2020
Background: Candida species are the most common cause of fungal infections worldwide. Candida albicans has been the most common causative agent until recent past but frequency of non-albicans Candida (NAC) species is on the rise.
Ratna Shukla, Sukrutha Gopal Reddy, Anil Kumar Bilolikar   +2 more
doaj   +1 more source