Optical modulation of high-affinity biomolecules function via photochromic dyes : a step towards an artificial control of biological activity [PDF]
, 2008 Prior to this study, there has yet to be a clear demonstration of an artificial control of antibody affinity via photochromic dyes. The research described in this thesis sets out to address this by investigating photochromic dyes and their subsequent ...
Annan, Bernard Derek
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Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]
, 1974 The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
An escherichia coli vaccine co-expressing listeriolysin-O and tumour antigen in cancer immunotherapy and the mechanisms of immune regulation [PDF]
, 2009 PhDSome recombinant bacterial strains have been shown to be very efficient in experimental therapies against cancer in rodent models. Amongst them is an E. coli that expresses the Listeriolysin-O protein (LLO) and a model tumour antigen ovalbumin (OVA)
Dai, Ming-Shen
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[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Antibody-antigen reactions in allergy. [PDF]
, 1959 Antibody-antigen interactions characterize both the immune and allergic conditions. The antibodies responsible for the allergic condition have been credited with several unique characteristics both to explain the difference in the clinical manifestation ...
Gordon, Julius.
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In vivo and in vitro studies of immune responses induced by normal or attenuated 'Schistosoma mansoni' schistosomula [PDF]
A schistosome vaccine would be of great value in controlling schistosomiasis. Exposure of experimental animals to live gamma-irradiated cercariae (GI) is highly effective and although not logistically feasible for ...
Mansour, Nuha Ramsis Nasief
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Antigen and antibody.jpg [PDF]
, 2016 Immunoassay is a biochemical method that identifies and quantifies unknown analytes (protein, lipid, nucleic acid etc.) in solution (serum, urine etc.) using antibody-antigen reactions.
Yudong Lu (2618959)
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Role of antibodies and T cells in pigeon fanciers' lung [PDF]
: Introduction: Pigeon fanciers’ lung (PFL) is one of the most common forms of hypersensitivity pneumonitis (HP) in the UK. Generally it is considered that PFL is caused by immune complexes, however, this does not explain why some fanciers are ...
Nademi, Zohreh
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