Results 111 to 120 of about 3,851,506 (357)
Carbohydrate moieties of major histocompatibility complex class I alloantigens are not required for their recognition by T lymphocytes. [PDF]
, 1985 The ability to generate specific cytotoxic responses using purified major histocompatibility complex (MHC) antigen in liposomes has made it possible to directly assess the importance of class I carbohydrate moieties in T cell recognition of alloantigen ...
Goldstein, SA, Mescher, MF
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Antibody signatures elicited by potent and subpotent whole-cell pertussis vaccines in mice
Microbiology SpectrumInactivated, whole-cell pertussis (wP) vaccines remain at the frontline in the global fight against the resurgence of whooping cough, especially in low- and middle-income countries. However, the reliance on the intracerebral mouse potency test (ic-MPT or
Yetunde Adewunmi +10 more
doaj +1 more source
Cross-reactivity of autoreactive T cells with MBP and viral antigens in patients with MS [PDF]
, 2011 Weizhi Cheng
openalex +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
HLA Class I (A and B) Allele Polymorphism in a Moroccan Population Infected with Hepatitis C Virus
Current Issues in Molecular BiologyHepatitis C virus (HCV) infection is one of the major health burdens worldwide. Its course depends on the virus itself and the host’s immune responses.
Safa Machraoui +6 more
doaj +1 more source
Studies on Antigen-Induced Arthritis in Mice [PDF]
, 1977 Dieter Brackertz +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A General Theory for Direct Quantitative Analysis of Antigen [PDF]
, 2012 A theory for direct quantitative analysis of an antigen is proposed. It is based on a potential homogenous immunoreaction system. It establishes an equation to describe the concentration change of the antigen and antibody complex.
Gan, Feng +3 more
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