Results 231 to 240 of about 3,665,754 (387)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Tumor markers and multimodal magnetic resonance imaging in predicting rectal cancer stage and differentiation. [PDF]

World J Gastrointest Oncol
Wang P, Han J, Zhao WN, Wu F, Zhang SH, Huang YJ.   +5 more
europepmc   +1 more source

The Precipitating Antigens of Friedlander's Bacillus

, 1953
M. J. Pickett, V. J. Cabelli
openalex   +1 more source

Immunochemical Studies on Tobacco Mosaic Virus. VI. The Effect of Papain on the Antibody-Antigen Complex [PDF]

, 1950
Saul Malkiel
openalex   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Optimizing PBMC Cryopreservation and Utilization for ImmunoSpot^® Analysis of Antigen-Specific Memory B Cells. [PDF]

Vaccines (Basel)
Becza N, Yao L, Lehmann PV, Kirchenbaum GA.   +3 more
europepmc   +1 more source

The Cysteine-Inactivated Proteinase ( -antigen) of Clostridium histolyticum

, 1958
C. L. Oakley, G. Harriet Warrack
openalex   +1 more source

Antigenic Analysis of Variants of B. Paradysenteriae and the Serological Relation of One Variant to B. Morgani [PDF]

, 1932
G. M. Mackenzie, Louise N. Batt
openalex   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Preliminary Report of Histoplasmin and Other Antigen Sensitivity in North Carolina

, 1951
Robert J. Murphy, William M. Peck, Blanche Vincent   +2 more
openalex   +2 more sources