Results 31 to 40 of about 3,619,273 (388)
Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]
, 2016 Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim +4 more
core +2 more sources
Central Asian Journal of Global Health, 2014 Introduction. The treatment of destructive inflammatory joint diseases (arthropathies) is one of the issues of current interest in modern medicine.
Marzhan Kaulambayeva +2 more
doaj +1 more source
Frontiers in Genetics, 2020 The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón +6 more
doaj +1 more source
The biological activity of soluble antigen-antibody complexes: II. Physical properties of soluble complexes having skin-irritating activity [PDF]
, 1959 Previous work by Germuth and McKinnon (1), Trapani et al. (2), and ourselves (3) has established the fact that soluble antigen-antibody complexes formed in excess antigen can, (a) induce symptoms similar to anaphylaxis, (b) cause contraction of isolated ...
Campbell, Dan H. +2 more
core +1 more source
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
New England Journal of Medicine, 2011 We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with CD137 (a costimulatory receptor in T cells [4-1BB]) and CD3-zeta (a signal-transduction component of the T-cell antigen ...
D. Porter +4 more
semanticscholar +1 more source
Nanobody based dual specific CARs [PDF]
, 2018 Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas.
Abken, Hinrich +8 more
core +2 more sources
npj Vaccines, 2023 This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with either Army ...
Shikha Shrivastava +27 more
doaj +1 more source
B lymphocytes secrete antigen-presenting vesicles
Journal of Experimental Medicine, 1996 Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II- enriched compartment), that harbors newly synthesized MHC class II molecules in transit to the plasma membrane. MIICs have a
G. Raposo +6 more
semanticscholar +1 more source
Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]
, 2018 Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J +6 more
core +2 more sources
Journal of Immunology, 1984 The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present investigation was to clarify whether the Ki-67 nuclear antigen is restricted in its expression to certain phases of the cell cycle.
J. Gerdes +5 more
semanticscholar +1 more source