Results 31 to 40 of about 2,572,697 (149)

Innovations in the Insect Cell Expression System for Industrial Recombinant Vaccine Antigen Production

Vaccines, 2021
The insect cell expression system has previously been proposed as the preferred biosecurity strategy for production of any vaccine, particularly for future influenza pandemic vaccines.
Manon M. J. Cox
doaj   +1 more source

Serotyping and Cross-Reactivity’s Between Different Pseudomonas aeruginosa Isolates Prevalent in Iran

Iranian Journal of Microbiology, 2010
Background and Objectives: 300 Pseudomonas aeruginosa strains were isolated from hospitalized patients in Iran. Using international antigenic typing system (IATS) antibodies, all strains were classified into 16 serotypes while serotype 14 was not ...
H Ahmadi, S Malekian, B Tabaraie, D Norouzian, F Poormirza-gholi, M Nejati, MH Hedayati, MR Beik Mohammadi, A Behnoodi, M Izadpanahi   +9 more
doaj  

Identification of Novel Serodiagnostic Signatures of Typhoid Fever Using a Salmonella Proteome Array

Frontiers in Microbiology, 2017
Current diagnostic tests for typhoid fever, the disease caused by Salmonella Typhi, are poor. We aimed to identify serodiagnostic signatures of typhoid fever by assessing microarray signals to 4,445 S.
Thomas C. Darton, Thomas C. Darton, Thomas C. Darton, Stephen Baker, Arlo Randall, Sabina Dongol, Abhilasha Karkey, Merryn Voysey, Merryn Voysey, Michael J. Carter, Claire Jones, Krista Trappl, Jozelyn Pablo, Chris Hung, Andy Teng, Adam Shandling, Tim Le, Cassidy Walker, Douglas Molina, Jason Andrews, Amit Arjyal, Buddha Basnyat, Andrew J. Pollard, Christoph J. Blohmke   +23 more
doaj   +1 more source

The Frequency of HLA-A, HLA-B, and HLA-DRB1 Alleles in Patients with Acute Lymphoblastic Leukemia in the Turkish Population: A Case-Control Study

Turkish Journal of Hematology, 2016
We studied the frequencies of human leukocyte antigen alleles (A, B, and DRB1) in 90 patients with acute lymphoblastic leukemia (ALL) and then compared them with 126 controls in this study. Although the frequencies of the A*03 allele, the DRB1*03 allele,
Türkan Patıroğlu, H. Haluk Akar
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Diagnostic validation of novel Borrelia antigens discovered by whole-proteome microarray: Advancing early detection and test of cure for Lyme disease

Cell Reports Medicine
Summary: Lyme disease serodiagnosis has limited early sensitivity and cannot distinguish active from past infections. To address this, we screen a Borrelia afzelii whole-proteome microarray (1,296 proteins) using human (n = 149) and murine (n = 32) sera.
Abhijeet Nayak, M.E. Baarsma, Jacqueline A. van Eck, Arlo Z. Randall, Jeanine Ursinus, Andy A. Teng, Jozelyn V. Pablo, Chris Hung, Doris U.M. Wopereis, Freek van de Schoor, Calin D. Popa, Cees C. van den Wijngaard, Bart-Jan Kullberg, Leo A.B. Joosten, Herman Kuiper, Joseph J. Campo, Xiaouw Liang, Joppe W. Hovius   +17 more
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Human Primary Macrophages Derived In Vitro from Circulating Monocytes Comprise Adherent and Non-Adherent Subsets with Differential Expression of Siglec-1 and CD4 and Permissiveness to HIV-1 Infection

Frontiers in Immunology, 2017
Macrophages are a major target for human immunodeficiency virus type 1 (HIV-1) infection. However, macrophages are largely heterogeneous and may exhibit differences in permissiveness to HIV-1 infection.
Ousman Jobe, Ousman Jobe, Jiae Kim, Jiae Kim, Eric Tycksen, Sayali Onkar, Sayali Onkar, Nelson L. Michael, Carl R. Alving, Mangala Rao   +9 more
doaj   +1 more source

Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model

Frontiers in Immunology, 2017
Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP) models for studying human immunodeficiency virus (HIV)-1 biology and pathogenesis.
Jiae Kim, Jiae Kim, Kristina K. Peachman, Kristina K. Peachman, Ousman Jobe, Ousman Jobe, Elaine B. Morrison, Atef Allam, Atef Allam, Linda Jagodzinski, Sofia A. Casares, Mangala Rao   +11 more
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Generic methodology to prevent food contamination by soil born legacy POPs in free range livestock

Heliyon
Government monitoring commonly includes regulating POPs in animal feed and products of animal origin, with many countries setting Maximum Residue Levels (MRLs) to ensure safe tolerable concentrations.
Farida Amutova, Matthieu Delannoy, Araylym Akhatzhanova, Nurlan Akhmetsadykov, Gaukhar Konuspayeva, Stefan Jurjanz   +5 more
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Antigenic Variability [PDF]

Frontiers in Immunology, 2020
Protective vaccines for hypervariable pathogens are urgently needed. It has been proposed that amputating highly variable epitopes from vaccine antigens would induce the production of broadly protective antibodies targeting conserved epitopes. However, so far, these approaches have failed, partially because conserved epitopes are occluded in vivo and ...
openaire   +3 more sources

Dynamics of α-D-mannose carbohydrate-binding sites distribution in rats’ pancreatic structures during the morpho-functional formation

Zaporožskij Medicinskij Žurnal, 2017
Recently, the pathology of pancreas in children is observed more frequently. Precursors of inflammation development in pancreas are dysfunctional disorders, which include conditions accompanied by changes in pancreatic secretion in the absence of ...
N. V. Hrinivetska, Yu. A. Burega, I. M. Maslova   +2 more
doaj   +1 more source