Results 31 to 40 of about 2,264,666 (258)
Molecular tug of war reveals adaptive potential of an immune cell repertoire [PDF]
arXiv, 2022 The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B lymphocytes expressing high-affinity antigen receptors.
arxiv
The biological activity of soluble antigen-antibody complexes: II. Physical properties of soluble complexes having skin-irritating activity [PDF]
, 1959 Previous work by Germuth and McKinnon (1), Trapani et al. (2), and ourselves (3) has established the fact that soluble antigen-antibody complexes formed in excess antigen can, (a) induce symptoms similar to anaphylaxis, (b) cause contraction of isolated ...
Campbell, Dan H. +2 more
core +1 more source
Frontiers in Immunology, 2022 Co-stimulation is critical to the function of chimeric antigen receptor (CAR) T-cells. Previously, we demonstrated that dual co-stimulation can be effectively harnessed by a parallel (p)CAR architecture in which a CD28-containing second generation CAR is
Leena Halim +13 more
doaj +1 more source
The effects of symmetry on the dynamics of antigenic variation [PDF]
J. Math. Biol. 66, 115-137 (2013), 2012 In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in malaria, we show how many of the observed dynamical regimes can be explained in terms of the symmetry of ...
arxiv +1 more source
Nanobody based dual specific CARs [PDF]
, 2018 Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas.
Abken, Hinrich +8 more
core +2 more sources
Наукові горизонтиThe purpose of the study was to investigate the cultural method of the diagnosis of Chlamydophila abortus. For this purpose, laboratory diagnosis of pathological material from the farm was carried out at the LLP Research and Production Enterprise ...
Yerkin Krykbayev +4 more
doaj +1 more source
Preparation and evaluation of Salmonella Enteritidis antigen conjugated with nanogold for screening of poultry flocks [PDF]
Veterinary World, 2017 Aim: The present work aimed to develop lateral flow immunochromatographic strip (ICS) test for detection of Salmonella Enteritidis (SE) specific antibodies in chicken sera.
Hazem Mohammed Ibrahim +3 more
doaj +1 more source
Antigen-presenting cells and antigen presentation in tertiary lymphoid organs [PDF]
, 2016 Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Bedaj, Marija +3 more
core +1 more source
Наукові горизонтиThe study aimed to develop and evaluate an antibody quality improvement method to improve the accuracy and efficiency of chlamydia diagnosis in horses.
Nurtas Tyrsynbayev +4 more
doaj +1 more source
The role of microbial enzymes β-glucanase and α-amylase in optimising feed production for poultry
Наукові горизонтиWith the increase in world population and higher consumption of poultry meat, the need for efficient feed production to ensure high quality and quantity of products is increasing.
Zhanar Narmuratova +4 more
doaj +1 more source