Results 51 to 60 of about 3,174,163 (298)

Antigen - presentation by vascular endothelium : its role for CTL - mediated vascular injury [PDF]

, 2008
Background: EC express and present MHC class I restricted peptide antigens and due to the exposed position may be targeted by antigen-specific CTL. We wished to explore the type of vascular injury that is mediated by peptidespecific CTL in vivo when EC ...
Wang, Xueya
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci

Nature Communications
Streptococcus pneumoniae (pneumococcus) is a nasopharyngeal commensal and respiratory pathogen. This study characterises the immunoglobulin G (IgG) repertoire recognising pneumococci from birth to 24 months old (mo) in a prospectively-sampled cohort of ...
Nicholas J. Croucher, Joseph J. Campo, Timothy Q. Le, Jozelyn V. Pablo, Christopher Hung, Andy A. Teng, Claudia Turner, François Nosten, Stephen D. Bentley, Xiaowu Liang, Paul Turner, David Goldblatt   +11 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A novel pan-proteome array for high-throughput profiling of the humoral response to Treponema pallidum

iScience
Summary: Given the resurgence of syphilis, research endeavors to improve current assays for serological diagnosis and management of this disease are a priority.
Joseph J. Campo, Emily Romeis, Amit Oberai, Jozelyn V. Pablo, Christopher Hung, Andy A. Teng, Adam D. Shandling, Amber Phan, Austin M. Haynes, Lorenzo Giacani   +9 more
doaj   +1 more source

Immune-histochemical indicators of the morpho-functional state of the thyroid gland in norm and after prenatal antigenic exposure

Medičnì Perspektivi, 2021
During the individual development and exposure to infectious agents of the organism, the structural components of the thyroid gland can change significantly.
O.V. Fedosieieva
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Bioaccessibility of Organochlorine Pesticides in Contaminated Soil: A Poultry-Informed In Vitro Gastrointestinal Model

Biology
Free-ranging poultry ingest 4–30 g of soil per day, making soil a significant route of organochlorine pesticide (OCP) exposure in agricultural areas with legacy contamination. However, total soil concentrations overestimate actual exposure.
Arailym Akhatzhanova, Farida Amutova, Moldir Nurseitova, Nurlan Akhmetsadykov, Yerbolat Sailaukhanuly, Gaukhar Konuspayeva, Stefan Jurjanz   +6 more
doaj   +1 more source

Dendritic Cells and Their Multiple Roles during Malaria Infection

Journal of Immunology Research, 2016
Dendritic cells (DCs) play a central role in the initiation of adaptive immune responses, efficiently presenting antigens to T cells. This ability relies on the presence of numerous surface and intracellular receptors capable of sensing microbial ...
Kelly N. S. Amorim, Daniele C. G. Chagas, Fernando B. Sulczewski, Silvia B. Boscardin   +3 more
doaj   +1 more source

Immune and Oxidative Response against Sonicated Antigen of Mycoplasma capricolum subspecies capripneumonia—A Causative Agent of Contagious Caprine Pleuropneumonia

Microorganisms, 2022
Vaccines are vital for prevention and control of mycoplasma diseases. The exploration of a vaccine candidate for the development of a vaccine is imperative. The present study envisages the evaluation of immune and oxidative response against an adjuvanted,
Rather Izhar Ul Haq, Oveas Rafiq Parray, Qurat Ul Ain Nazir, Riyaz Ahmed Bhat, Showkat Ahmad Shah, Majid Shafi Kawoosa, Ali A. Rabaan, Mohammed Aljeldah, Basim R. Al Shammari, Mohammed S. Almogbel, Nada Alharbi, Reem Alrashoudi, Amal A. Sabour, Rana A. Alaeq, Maha A. Alshiekheid, Saleh A. Alshamrani, Aqel Albutti, Ameen S.S. Alwashmi, Kuldeep Dhama, Mohd. Iqbal Yatoo   +19 more
doaj   +1 more source