Results 71 to 80 of about 3,851,506 (357)

Assessment of T Cell Receptor Complex Expression Kinetics in Natural Killer Cells

Current Issues in Molecular Biology, 2022
Among the polypeptides that comprise the T cell receptor (TCR), only CD3ζ is found in Natural Killer (NK) cells, where it transmits signals from activating receptors such as CD16 and NKp46.
Khder H. Rasul, Alamdar Hussain, Hazel Reilly, Maria Karvouni, Carin I. M. Dahlberg, Mustafa S. Al-Attar, Arnika K. Wagner, Evren Alici, Dara K. Mohammad   +8 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella

mSphere
Shigella is a leading cause of diarrheal morbidity and mortality in young children from low- and middle-income countries. Here, we aimed to verify the ability of the generalized modules for membrane antigens (GMMA)-based Shigella sonnei candidate vaccine
Arlo Z. Randall, Valentino Conti, Usman Nakakana, Xiaowu Liang, Andy A. Teng, Antonio Lorenzo Di Pasquale, Melissa Kapulu, Robert Frenck, Odile Launay, Pietro Ferruzzi, Antonella Silvia Sciré, Elisa Marchetti, Christina Obiero, Jozelyn V. Pablo, Joshua Edgar, Philip Bejon, Adam D. Shandling, Joseph J. Campo, Angela Yee, Laura B. Martin, Audino Podda, Francesca Micoli   +21 more
doaj   +1 more source

Major Surface Antigens in Zoonotic Babesia

Pathogens, 2022
Human babesiosis results from a combination of tick tropism for humans, susceptibility of a host to sustain Babesia development, and contact with infected ticks.
Stephane Delbecq
doaj   +1 more source

Carcinoembryonic Antigen Gene Family [PDF]

, 1991
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin supergene family and can be divided into two main subgroups based on sequence comparisons.
Accili, Ahnen, Anderson, Arakawa, Arakawa, Audette, Aurivillius, Barnett, Barnett, Barnett, Barnett, Barnett, Barthels, Beatty, Beauchemin, Beauchemin, Beauchemin, Beidler, Benchimol, Berling, Berling, Bhattacharya-Chatterjee, Biggin, Bischof, Bischoff-Delaloye, Bohn, Bordes, Borjigin, Boucher, Boucher, Buchegger, Buchegger, Burtin, Börmer, Capecchi, Chakrabarty, Chakrabarty, Chan, Chan, Chandrasekaran, Chou, Chou, Chu, Cordon, Cournoyer, Cross, Cunningham, DeRobertis, Dustin, Edelman, Edwards, Egan, Fantini, Feizi, Fiebig, Freyer, Fritsch, Fritsche, Fritz Grunert, Gold, Gold, Goldenberg, Goldenberg, Greiner, Greiner, Grosveld, Grunert, Grunert, Guadagni, Hager, Hammarström, Haniford, Hansson, Hardman, Hass, Hefta, Hefta, Hefta, Hemperly, Higashide, Hinoda, Hinoda, Hinoda, Hostetter, Huang, Huitric, Hwang, Inazawa, Jean, John A. Thompson, Jones, Kamarck, Kasuga, Khan, Khan, Khan, Knapp, Kobata, Kodelja, Kolbinger, Kudo, Kupchik, Kuroki, Kuroki, Kuroki, Kuroki, Kuroki, Kuroki, Kuroki, Kurroki, Lai, Leon, Leslie, Leusch, Lewis, Lin, Lin, Lin, Lisanti, Losman, Mach, Margolis, Margolis, Martin, Matsuoka, McDonald, McLenachan, Monden, Mount, Nagata, Neumaier, Neumaier, Neumaier, Nichols, Niemann, Niemann, Niles, Novak-Hofer, Ocklind, Odin, Ogilvie, Oikawa, Oikawa, Oikawa, Oikawa, Oikawa, Paxton, Perkins, Perrotti, Pignatelli, Proudfoot, Ravetch, Ravetch, Rebstock, Rees-Jones, Rojas, Rooney, Rosen, Rosen, Rudert, Rudert, Ruoslahti, Sack, Salzer, Sato, Saunders, Schmid, Schonk, Schrewe, Schrewe, Schwarz, Schwarz, Sell, Sewell, Sharkey, Shively, Siepen, Slightom, Smale, Soeller, Staunton, Staunton, Streydio, Streydio, Streydio, Svenberg, Svenberg, Takami, Takeichi, Takeichi, Tatarinov, Tawaragi, Terry, Thomas, Thomas, Thompson, Thompson, Thompson, Thompson, Thompson, Tingström, Toribara, Toribara, Toth, Toth, Tran, Tsao, Tsujisaki, Tsujisaki, Tuan, Turbide, Van der Schoot, Van der Schoot, Von Kleist, Von Kleist, Von Kleist, Von Kleist, Vorličková, Wallner, Watanabe, Watanabe, Watt, Willcocks, Willcocks, Williams, Williams, Williams, Wolfgang Zimmermann, Yamaguchi, Yarden, Zheng, Zhou, Zimmermann, Zimmermann, Zimmermann, Zoubir, Öbrink   +236 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Serotyping and Cross-Reactivity’s Between Different Pseudomonas aeruginosa Isolates Prevalent in Iran

Iranian Journal of Microbiology, 2010
Background and Objectives: 300 Pseudomonas aeruginosa strains were isolated from hospitalized patients in Iran. Using international antigenic typing system (IATS) antibodies, all strains were classified into 16 serotypes while serotype 14 was not ...
H Ahmadi, S Malekian, B Tabaraie, D Norouzian, F Poormirza-gholi, M Nejati, MH Hedayati, MR Beik Mohammadi, A Behnoodi, M Izadpanahi   +9 more
doaj  

A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes [PDF]

, 1989
Peptides that are antigenic for T lymphocytes are ligands for two receptors, the class I or II glycoproteins that are encoded by genes in the major histocompatibility complex, and the idiotypic / chain T-cell antigen receptor1–9. That a peptide must bind
A Sette, A Townsend, B Babbitt, C DeLisi, DW Thomas, GM Keil, H Margalit, H Volkmer, HC Bodmer, JB Rothbard, JB Rothbard, Jonathan B. Rothbard, M Del Val, Matthias J. Reddehase, MBA Oldstone, MF Good, MJ Reddehase, MJ Reddehase, MJ Reddehase, MM Davis, N Shastri, P Marrack, PJ Bjorkman, PM Allen, R Shimonkevitz, RH Schwartz, RH Schwartz, RM Zinkernagel, S Buus, UH Koszinowski, Ulrich H. Koszinowski   +30 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Identification of Novel Serodiagnostic Signatures of Typhoid Fever Using a Salmonella Proteome Array

Frontiers in Microbiology, 2017
Current diagnostic tests for typhoid fever, the disease caused by Salmonella Typhi, are poor. We aimed to identify serodiagnostic signatures of typhoid fever by assessing microarray signals to 4,445 S.
Thomas C. Darton, Thomas C. Darton, Thomas C. Darton, Stephen Baker, Arlo Randall, Sabina Dongol, Abhilasha Karkey, Merryn Voysey, Merryn Voysey, Michael J. Carter, Claire Jones, Krista Trappl, Jozelyn Pablo, Chris Hung, Andy Teng, Adam Shandling, Tim Le, Cassidy Walker, Douglas Molina, Jason Andrews, Amit Arjyal, Buddha Basnyat, Andrew J. Pollard, Christoph J. Blohmke   +23 more
doaj   +1 more source