Results 41 to 50 of about 3,846,927 (338)

Panproteome-wide analysis of antibody responses to whole cell pneumococcal vaccination

eLife, 2018
Pneumococcal whole cell vaccines (WCVs) could cost-effectively protect against a greater strain diversity than current capsule-based vaccines. Immunoglobulin G (IgG) responses to a WCV were characterised by applying longitudinally-sampled sera, available
Joseph J Campo, Timothy Q Le, Jozelyn V Pablo, Christopher Hung, Andy A Teng, Hervé Tettelin, Andrea Tate, William P Hanage, Mark R Alderson, Xiaowu Liang, Richard Malley, Marc Lipsitch, Nicholas J Croucher   +12 more
doaj   +1 more source

A novel interdigitated capacitor based biosensor for detection of cardiovascular risk marker [PDF]

, 2009
C-reactive protein (CRP) is a potential biomarker whose elevated levels in humans determine cardiovascular disease risk and inflammation. In this study, we have developed a novel capacitive biosensor for detection of CRP-antigen using capacitor with ...
Davidson, Jimmy L., Gürbüz, Yaşar, Kang, Weng P., Qureshi, Anjum   +3 more
core   +1 more source

Carcinoembryonic Antigen Gene Family [PDF]

, 1991
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin supergene family and can be divided into two main subgroups based on sequence comparisons.
Accili, Ahnen, Anderson, Arakawa, Arakawa, Audette, Aurivillius, Barnett, Barnett, Barnett, Barnett, Barnett, Barthels, Beatty, Beauchemin, Beauchemin, Beauchemin, Beidler, Benchimol, Berling, Berling, Bhattacharya-Chatterjee, Biggin, Bischof, Bischoff-Delaloye, Bohn, Bordes, Borjigin, Boucher, Boucher, Buchegger, Buchegger, Burtin, Börmer, Capecchi, Chakrabarty, Chakrabarty, Chan, Chan, Chandrasekaran, Chou, Chou, Chu, Cordon, Cournoyer, Cross, Cunningham, DeRobertis, Dustin, Edelman, Edwards, Egan, Fantini, Feizi, Fiebig, Freyer, Fritsch, Fritsche, Fritz Grunert, Gold, Gold, Goldenberg, Goldenberg, Greiner, Greiner, Grosveld, Grunert, Grunert, Guadagni, Hager, Hammarström, Haniford, Hansson, Hardman, Hass, Hefta, Hefta, Hefta, Hemperly, Higashide, Hinoda, Hinoda, Hinoda, Hostetter, Huang, Huitric, Hwang, Inazawa, Jean, John A. Thompson, Jones, Kamarck, Kasuga, Khan, Khan, Khan, Knapp, Kobata, Kodelja, Kolbinger, Kudo, Kupchik, Kuroki, Kuroki, Kuroki, Kuroki, Kuroki, Kuroki, Kuroki, Kurroki, Lai, Leon, Leslie, Leusch, Lewis, Lin, Lin, Lin, Lisanti, Losman, Mach, Margolis, Margolis, Martin, Matsuoka, McDonald, McLenachan, Monden, Mount, Nagata, Neumaier, Neumaier, Neumaier, Nichols, Niemann, Niemann, Niles, Novak-Hofer, Ocklind, Odin, Ogilvie, Oikawa, Oikawa, Oikawa, Oikawa, Oikawa, Paxton, Perkins, Perrotti, Pignatelli, Proudfoot, Ravetch, Ravetch, Rebstock, Rees-Jones, Rojas, Rooney, Rosen, Rosen, Rudert, Rudert, Ruoslahti, Sack, Salzer, Sato, Saunders, Schmid, Schonk, Schrewe, Schrewe, Schwarz, Schwarz, Sell, Sewell, Sharkey, Shively, Siepen, Slightom, Smale, Soeller, Staunton, Staunton, Streydio, Streydio, Streydio, Svenberg, Svenberg, Takami, Takeichi, Takeichi, Tatarinov, Tawaragi, Terry, Thomas, Thomas, Thompson, Thompson, Thompson, Thompson, Thompson, Tingström, Toribara, Toribara, Toth, Toth, Tran, Tsao, Tsujisaki, Tsujisaki, Tuan, Turbide, Van der Schoot, Van der Schoot, Von Kleist, Von Kleist, Von Kleist, Von Kleist, Vorličková, Wallner, Watanabe, Watanabe, Watt, Willcocks, Willcocks, Williams, Williams, Williams, Wolfgang Zimmermann, Yamaguchi, Yarden, Zheng, Zhou, Zimmermann, Zimmermann, Zimmermann, Zoubir, Öbrink   +236 more
core   +1 more source

SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses

npj Vaccines, 2021
The emergence of variants of concern, some with reduced susceptibility to COVID-19 vaccines underscores consideration for the understanding of vaccine design that optimizes induction of effective cellular and humoral immune responses.
Joshua M. Carmen, Shikha Shrivastava, Zhongyan Lu, Alexander Anderson, Elaine B. Morrison, Rajeshwer S. Sankhala, Wei-Hung Chen, William C. Chang, Jessica S. Bolton, Gary R. Matyas, Nelson L. Michael, M. Gordon Joyce, Kayvon Modjarrad, Jeffrey R. Currier, Elke Bergmann-Leitner, Allison M. W. Malloy, Mangala Rao   +16 more
doaj   +1 more source

Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity [PDF]

, 2012
Decline of cell-mediated immunity is often attributed to decaying T-cell numbers and their distribution in peripheral organs. This study examined the hypothesis that qualitative as well as quantitative changes contribute to the declining efficacy of CD8+
Alexander-Miller, Almeida, Appay, Berger, Betts, Bosselut, Cerundolo, Gallimore, Gorman, Hansen, Hollander, Homann, Jelley-Gibbs, Jenkins, Jones, Jones, Judge, Karrer, Kattan, Kedzierska, Kim, Kohlmeier, Lefranc, Liang, Moffat, Neveu, Norbury, Powell, Price, Quigley, Rangel-Moreno, Richards, Roberts, Schluns, Tan, Tough, Trautmann, Valkenburg, Valkenburg, Woodland, Wooldridge, Zammit   +41 more
core   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Body Measurements and Body Condition Scoring in Bactrian Camels

Animals
Body measurements are used regularly to describe phenotypes or the weight of animals. However, little data describe the age effect on the different measurements.
Bernard Faye, Shynar Akhmetsadykova, Moldir Akhmetzhanova, Zauresh Bilal, Zhaidar Musayev, Gaukhar Konuspayeva   +5 more
doaj   +1 more source

Regulation of B cell fate by chronic activity of the IgE B cell receptor. [PDF]

, 2016
IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR).
Allen, Christopher DC, Chen, Xiangjun, Liu, Wanli, Robinson, Marcus J, Smith, Geoffrey A, Taunton, Jack, Yang, Zhiyong   +6 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal ColonSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Most knowledge about gastrointestinal (GI)-tract dendritic cells (DC) relies on murine studies where CD103+ DC specialize in generating immune tolerance with the functionality of CD11b+/− subsets being unclear.
David Bernardo, Lydia Durant, Elizabeth R. Mann, Elizabeth Bassity, Enrique Montalvillo, Ripple Man, Rakesh Vora, Durga Reddi, Fahri Bayiroglu, Luis Fernández-Salazar, Nick R. English, Simon T.C. Peake, Jon Landy, Gui H. Lee, George Malietzis, Yi Harn Siaw, Aravinth U. Murugananthan, Phil Hendy, Eva Sánchez-Recio, Robin K.S. Phillips, Jose A. Garrote, Paul Scott, Julian Parkhill, Malte Paulsen, Ailsa L. Hart, Hafid O. Al-Hassi, Eduardo Arranz, Alan W. Walker, Simon R. Carding, Stella C. Knight   +29 more
doaj   +1 more source