Results 61 to 70 of about 4,473,616 (249)

Comparing the performance of urine and copro-antigen detection in evaluating Opisthorchis viverrini infection in communities with different transmission levels in Northeast Thailand. [PDF]

PLoS Neglected Tropical Diseases, 2019
To combat and eventually eliminate the transmission of the liver fluke Opisthorchis viverrini, an accurate and practical diagnostic test is required.
Chanika Worasith, Chompunoot Wangboon, Kunyarat Duenngai, Nadda Kiatsopit, Kulthida Kopolrat, Anchalee Techasen, Jiraporn Sithithaworn, Narong Khuntikeo, Watcharin Loilome, Nisana Namwat, Puangrat Yongvanit, Elizabeth J Carlton, Paiboon Sithithaworn   +12 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Identification and Characterization of Onchocerca volvulus Heat Shock Protein 70 (OvHSP70) as Novel Diagnostic Marker of Onchocerciasis in Human Urine

Pathogens
Despite several decades of mass drug administration and elimination-related activities, human onchocerciasis still represents a major parasitic threat in endemic regions.
Lum Abienwi Ambe, Elisabeth Limunga, Clarisse Engowei Mbah, Ngwewondo Adela, Ndumu Eric, Martha Ngoe, Bertrand Sone, Günter Lochnit, Julius Babila Tachu, Samuel Wanji, Anja Taubert, Carlos Hermosilla, Faustin Kamena   +12 more
doaj   +1 more source

Vesicles for Signal Amplification in a Biosensor for the Detection of Low Antigen Concentrations

Sensors, 2008
The sensitivity of biosensors is often not sufficient to detect diagnostically relevant biomarker concentrations. In this paper we have utilized a Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) to detect dissipative losses induced by the
Dorothee Grieshaber, Thomas Hirt, Janos Vörös, Victoria de Lange, Zhihua Lu   +4 more
doaj   +1 more source

COMPARATIVE STUDY FOR DIAGNOSIS OF FASCIOLIASIS IN CATTLE AND BUFFALOES BY ANTIBODY AND ANTIGEN DETECTION [PDF]

Assiut Veterinary Medical Journal, 2005
As a disease of domestic ruminants, fascioliasis is of considerable economic importance. The current research adopted two main methods for diagnosis of fascioliasis in naturally infected cattle and buffaloes.
EMAN H. ABDEL-RAHMAN, A.A. GHAZY
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Sensitivity and specificity of a urine circulating anodic antigen test for the diagnosis of Schistosoma haematobium in low endemic settings [PDF]

, 2015
Elimination of schistosomiasis as a public health problem and interruption of transmission in selected areas are key goals of the World Health Organization for 2025.
Cercamondi, Colin I, Corstjens, Paul LAM, Utzinger, Jürg, Corstjens, Paul L A M, Khalfan A Mohammed, Claudia J. de Dood (561700), David Rollinson (103447), David Rollinson, Khalfan A. Mohammed (39596), Rollinson, David, Corstjens, Paul L. A. M., Shaali M. Ame (159925), Stefanie Knopp, Artemis Koukounari (35316), Mohammed, Khalfan A, van Dam, Govert J., Claudia J de Dood, Govert J. van Dam (271055), de Dood, Claudia J., Dood, Claudia J. de, Ame, Shaali M., Dam, Govert J. van, Jürg Utzinger, Artemis Koukounari, Shaali M Ame, Ame, Shaali M, Koukounari, Artemis, Paul L. A. M. Corstjens (561702), de Dood, Claudia J, Govert J van Dam, Jürg Utzinger (39609), Paul L A M Corstjens, Ali, Said M, Stefanie Knopp (108848), van Dam, Govert J, Mohammed, Khalfan A., Corstjens, Paul L.A.M., Ali, Said M., Knopp, Stefanie, Said M Ali, Cercamondi, Colin I., Said M. Ali (130132), Colin I Cercamondi, Colin I. Cercamondi (738930)   +43 more
core   +2 more sources

Ammonium sulfate denatures transport medium less dependent on guanidinium isothiocyanate and enables SARS-CoV-2 RNA and antigen detection compatibility

Frontiers in Microbiology
IntroductionRapid identification of infected individuals through viral RNA or antigen detection followed by effective personal isolation is usually the most effective way to prevent the spread of a newly emerging virus.
Ge Liu, Jiapeng Xu, Yuanyuan Huang, Wei Ye, Jieyu Li, Ran Yan, Qiting Luo, Xinrui Zhou, Yingna Cai, Hanfang Jiang, Xiujing Lu, Kai Zheng, Zhendan He, Qinchang Zhu, Qinchang Zhu   +14 more
doaj   +1 more source