Results 81 to 90 of about 3,953,720 (287)

Animal models of anemia of inflammation: Methodological advances, limitations, and translational applications

Animal Models and Experimental Medicine, EarlyView.
Anemia of inflammation is a highly prevalent secondary anemia complicating chronic inflammatory diseases. Current animal models are categorized into sterile inflammation, disease‐specific, and genetically engineered models, with comparative analysis of their modeling principles, characteristic phenotypes, and translational advantages to elucidate core ...
Jiayi Cheng, Xiaodi Zhou, Qian Liu, Zixian Liu, Hao Wu   +4 more
wiley   +1 more source

Antigen induced arthritis in mice v1

Antigen-induced arthritis model of rheumatoid arthritis. The Udalova lab (University of Oxford) created this protocol, which Dr George Goodwin (King's College London) adapted. Expected results: Inflammation and swelling in the injected knee joint.
George Goodwin, Hayley L Eames, Franziska Denk, Irina Udalova   +3 more
openaire   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman, Shripad S. Hebbar, Rishikesh Balvalli, Manasa Nune   +3 more
wiley   +1 more source

The study of pharmacodynamics of a medicine based on humanized monoclonal antibodies against IL-17 in rabbit model of antigen-induced arthritis

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article contains scientific data on the assessment of specific activity of therapeutic humanized monoclonal antibodies against IL-17 in rabbit model of antigen-induced arthritis.
A. A. Nedorubov, A. V. Grachev, M. A. Varavko, E. L. Morozova   +3 more
doaj  

Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouse

Journal of Neuroinflammation, 2018
Objective The regulatory role of capsaicin-sensitive peptidergic sensory nerves has been shown in acute inflammation, but little is known about their involvement in T/B-cell driven autoimmune arthritis. This study integratively characterized the function
Ádám Horváth, Éva Borbély, Kata Bölcskei, Nikolett Szentes, Tamás Kiss, Mátyás Belák, Tibor Rauch, Tibor Glant, Róza Zákány, Tamás Juhász, Edina Karanyicz, Ferenc Boldizsár, Zsuzsanna Helyes, Bálint Botz   +13 more
doaj   +1 more source

Galectin 3 aggravates joint inflammation and destruction in antigen-induced arthritis

, 2011
Objective. Galectin 3, an endogenous beta galactoside-binding lectin, plays an important role in the modulation of immune responses. The finding that galectin 3 is present in the inflamed synovium in patients with rheumatoid arthritis suggests that the ...
Emil Andréasson, Annica Andersson, Mattias Magnusson, Andersson, Annica,, Brown, Kelly L,, Brown, Kelly,, Anna Karlsson, Karlström, Alexandra,, Sävman, Karin,, Ulrika Islander, Huamei Forsman, Karlsson, Anna,, Forsman, Huamei,, Magnusson, Mattias,, Andréasson, Emil,, Karin Önnheim, Önnheim, Karin,, Karin Sävman, Islander, Ulrika,, Alexandra Karlström, Kelly L. Brown   +20 more
core   +1 more source

Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice [PDF]

, 2013
Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury.
Imhof, Beat A., Aurrand-Lions, Michel, Michel Aurrand-Lions, Urs Christen, Pfeilschifter, Josef (Prof. Dr.), Pfeilschifter, Josef M, Hintermann, Edith, Beat A Imhof, Imhof, Beat, Christen, Selina, Kerstin Rose, Matthias G von Herrath, Rose, Kerstin, Christen, Urs, Herrath, Matthias G. von, von Herrath, Matthias G, Coppieters, Ken, Holdener, Martin, Monika Bayer, Ken Coppieters, Selina Christen, Martin Holdener, Edith Hintermann, Josef M Pfeilschifter, Bayer, Monika   +24 more
core   +2 more sources

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Chlamydia-induced reactive arthritis diagnosed during gout flares [PDF]

, 2019
Rationale:The pathology of gouty arthritis and reactive arthritis (ReA) partially overlaps, and both diseases are characterized by the production of inflammatory cytokines associated with the activation of monocytes and macrophages.
Shin-ya Kawashiri, Igawa, Takashi, Kawakami, Atsushi, Shimizu, Toshimasa, Remi Sumiyoshi, Iwamoto, Naoki, Hideki Nakamura, Takashi Igawa, Koga, Tomohiro, Tamai, Mami, Masataka Umeda, Nishino, Ayako, Umeda, Masataka, Tsuji, Sosuke, Tomoki Origuchi, Yushiro Endo, Sumiyoshi, Remi, Endo, Yushiro, Tomohiro Koga, Kawashiri, Shin-ya, Ayuko Takatani, Mami Tamai, Sosuke Tsuji, Origuchi, Tomoki, Fukui, Shoichi, Takatani, Ayuko, Nakamura, Hideki, Ayako Nishino, Atsushi Kawakami, Naoki Iwamoto, Ichinose, Kunihiro, Toshimasa Shimizu, Shoichi Fukui, Kunihiro Ichinose   +33 more
core   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source