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Antigen processing by the proteasome
Nature Reviews Molecular Cell Biology, 2001The proteasome is an essential part of our immune surveillance mechanisms: by generating peptides from intracellular antigens it provides peptides that are then 'presented' to T cells. But proteasomes--the waste-disposal units of the cell--typically do not generate peptides for antigen presentation with high efficiency.
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Antigen Processing/Presenting and Oncogenesis
Critical Reviews™ in Oncogenesis, 1997It has been established in recent years that a number of tumor cell types express tumor antigens, yet the host's immune system fails to recognize them. The antigen processing/presenting machinery, which plays a crucial role in generating an immune response, and possible causes for its inability of processing/presenting tumor antigens are reviewed ...
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Antigen processing movers and shakers
Nature Chemical Biology, 2018Monitoring MHC-I dynamics upon binding to its chaperone TAPBPR helps us understand how optimal peptide sequences are selected for presentation and coordinated with release of the chaperone from the ternary peptide–MHC-I–TAPBPR complex.
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Editorial overview: Antigen processing
Current Opinion in Immunology, 2016Christopher C, Norbury +1 more
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Antigen processing and recognition
Current Opinion in Immunology, 2005Clifford V, Harding, Jacques, Neefjes
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Antigen processing and presentation
Tissue Antigens, 1996F M, Brodsky, L, Lem, P A, Bresnahan
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Antigen processing and recognition
Current Opinion in Immunology, 2007Peter, van Endert, José A, Villadangos
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Antigen processing and recognition
Current Opinion in Immunology, 2001P, Cresswell, A, Lanzavecchia
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