Results 71 to 80 of about 10,676,235 (336)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Immunobiological Properties of Antigenic Preparations Streptococcus pneumoniae and their Mixtures

Эпидемиология и вакцинопрофилактика, 2022
Relevance. Type-specific immunity does not protect against infection with other pneumococcal serotypes. The phenomenon of the change of serotypes dominating the population of Streptococcus pneumoniae is known, in part due to the intensive recombination ...
M. M. Tokarskaya, E. A. Nayаnova, O. V. Nechaeva, S. A. Baranovskaya, O. M. Afanacyeva, D. S. Vorobyev, I. M. Gruber, E. A. Astashkina, N. N. Ovechko, I. B. Semenova, N. E. Yastrebova   +10 more
doaj   +1 more source

Galactosylsphingamides : new α-GalCer analogues to probe the F’-pocket of CD1d [PDF]

, 2017
Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for immune response modulation, as upon CD1d-mediated stimulation with KRN7000, a synthetic alpha-galactosylceramide, they produce a vast amount of cytokines.
Decruy, Tine, Elewaut, Dirk, Froeyen, Mathy, Guillaume, Joren, Janssens, Jonas, Remesh, Soumya G, Risseeuw, Martijn, Van Calenbergh, Serge, Wang, Jing, Zajonc, Dirk M   +9 more
core   +1 more source

Some antigenic properties of mammalian spermatozoa [PDF]

Proceedings of the Royal Society of London. Series B - Biological Sciences, 1949
Methods of testing sera for precipitins against seminal proteins, and for spermatozoal agglutinins are described. The influence of various factors on agglutination of rabbit and guinea-pig spermatozoa in hanging drop preparations has been investigated. In diluted normal sera agglutination of spermatozoa by their tails occurred rarely, and then only in ...
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins [PDF]

, 2018
Background: TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors.
Agüero, Fernan Gonzalo, Altcheh, Jaime Marcelo, Balouz, Virginia, Buscaglia, Carlos Andres, Camara, María de los Milagros, Campetella, Oscar Eduardo, Canepa, Gaspar Exequiel, Carlevaro, Giannina Alejandra, Carmona, Santiago Javier, Ciocchini, Andres Eduardo, Cortina, María Eugenia, Lobo, Mabel Maite, Melli, Luciano Jorge, Mucci, Juan Sebastián   +13 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epidemic season 2023–2024: the palette of ARVI pathogens in some territories of the Russian Federation and WHO regions

Вопросы вирусологии
The purpose of this work was to determine the characteristics of the circulation of acute respiratory viral infection (ARVI) pathogens during the epidemic season of 2023–2024 in the WHO regions and Russian Federation. Materials and methods.
Elena I. Burtseva, Nataliya V. Breslav, Evgenia A. Mukasheva, Kirill G. Krasnoslobodtsev, Elena S. Kirillova, Svetlana V. Trushakova, Irina A. Komarova, Elena L. Feodoritova, Anna D. Panova, Lidiya B. Kisteneva, Irina N. Khlopova, Irina S. Kruzhkova, Anastasia S. Krepkaia, Ekaterina O. Morozova, Anna V. Ignatieva, Andrey B. Komissarov, Igor N. Tyurin, Aleksey A. Samkov, Nataliya A. Antipjat   +18 more
doaj   +1 more source

Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites. [PDF]

, 1985
Three monoclonal antibodies that react with previously undefined antigenic determinants on the clathrin molecule have been produced and characterized. They were isolated from a fusion between myeloma cells and popliteal lymphocytes from SJL mice that had
Brodsky, Frances
core  

Tiling solutions for optimal biological sensing [PDF]

, 2015
Biological systems, from cells to organisms, must respond to the ever changing environment in order to survive and function. This is not a simple task given the often random nature of the signals they receive, as well as the intrinsically stochastic ...
Walczak, Aleksandra M.
core   +2 more sources