BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu +12 more
wiley +1 more source
Engineered Bacterial Membranes as Next-Generation Platforms for Cancer Immunotherapy. [PDF]
Malik HA +4 more
europepmc +1 more source
Detection of bacterial antigens in cerebrospinal fluid [PDF]
V, Jones, S, Roach, C, Hart
openaire +2 more sources
Active Bacterial Core Surveillance (ABCs) report : Emerging Infections Program Network : Neisseria meningitidis, 2019 [PDF]
Citation: Centers for Disease Control and Prevention. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Neisseria meningitidis, 2019. www.cdc.gov/abcs/downloads/NMEN_Surveillance_Report_2019.pdfPublication date from document
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Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin +10 more
wiley +1 more source
Integrated multi-omics strategy for screening novel protective antigens against Brucella melitensis and analysis of their immunogenicity. [PDF]
Dong Z, Li S, Guo J, Bao L.
europepmc +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Group A Streptococcus, 2020 [PDF]
Dataset version: Jul 2022 Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group A Streptococcus, 2020.Publication date from document ...
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Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li +11 more
wiley +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Streptococcus pneumoniae, 2018 [PDF]
Citation: Centers for Disease Control and Prevention. 2018. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2018.
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Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie +10 more
wiley +1 more source

