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Antibody therapy may be an alternative treatment option for infections caused by the multi-drug resistant (MDR) bacterium Acinetobacter baumannii. As A.
Gathoni Kamuyu +10 more
doaj +1 more source
Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin +50 more
core +2 more sources
Identification of Circulating Bacterial Antigens by
Detection of microbial antigens in clinical samples can lead to rapid diagnosis of an infection and administration of appropriate therapeutics. A major barrier in diagnostics development is determining which of the potentially hundreds or thousands of ...
Dana E. Nuti +13 more
doaj +1 more source
Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model. [PDF]
Pertussis is a highly infectious respiratory disease of humans caused by the bacterium Bordetella pertussis. Despite high vaccination coverage, pertussis has re-emerged globally.
Daan de Gouw +9 more
doaj +1 more source
Outer membrane vesicles: A bacterial-derived vaccination system
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj +1 more source
Target identification for prevention and therapy of "Salmonella" infections [PDF]
In this thesis we investigated maintenance requirements of Salmonella during chronic infections, and determined the relevant antigen properties that might facilitate the development of Salmonella vaccines. Overall, we wanted to achieve two goals: a)To
Barat, Somedutta
core +1 more source
Characterization of vaccine antigens of meningococcal serogroup W isolates from Ghana and Burkina Faso from 2003 to 2009 [PDF]
Neisseria meningitidis is a major cause of bacterial meningitis and a considerable health problem in the 25 countries of the 'African Meningitis Belt' that extends from Senegal in West Africa to Ethiopia in the East.
Calman MacLennan +11 more
core +1 more source
Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes +10 more
doaj +1 more source
Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical settings due to the emergence of antibiotic resistant strains and the lack of effective therapeutics.
Somshukla Chaudhuri +6 more
doaj +1 more source
Bacterial Spore Antigens: a Review [PDF]
SUMMARY: Agglutinogens and precipitinogens have been detected in the spores of many species of aerobic and anaerobic spore-formers and these antigens are distinct from those of the vegetative growth phases of the corresponding organisms. Spore antigens are heat resistant and antibody response is elicited by the injection of autoclaved spores into ...
openaire +2 more sources

