Results 21 to 30 of about 194,146 (265)

Comparative Reverse Vaccinology of Piscirickettsia salmonis, Aeromonas salmonicida, Yersinia ruckeri, Vibrio anguillarum and Moritella viscosa, Frequent Pathogens of Atlantic Salmon and Lumpfish Aquaculture

open access: yesVaccines, 2022
Marine finfish aquaculture is affected by diverse infectious diseases, and they commonly occur as co-infection. Some of the most frequent and prevalent Gram-negative bacterial pathogens of the finfish aquaculture include Piscirickettsia salmonis ...
Joy Chukwu-Osazuwa   +6 more
doaj   +1 more source

Cross-reactivity and sequence similarity between microbial transglutaminase and human tissue antigens

open access: yesScientific Reports, 2023
Microbial transglutaminase (mTG) is a bacterial survival factor, frequently used as a food additive to glue processed nutrients. As a result, new immunogenic epitopes are generated that might drive autoimmunity.
Aaron Lerner   +2 more
doaj   +1 more source

Recent Advances in Monoclonal Antibody-Based Approaches in the Management of Bacterial Sepsis

open access: yesBiomedicines, 2023
Sepsis is a life-threatening condition characterized by an uncontrolled inflammatory response to an infectious agent and its antigens. Immune cell activation against the antigens causes severe distress that mediates a strong inflammatory response in ...
Kusum Kharga   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Longevity of antibody and T-cell responses against outer membrane antigens of Orientia tsutsugamushi in scrub typhus patients

open access: yesEmerging Microbes and Infections, 2017
Scrub typhus, caused by Orientia tsutsugamushi infection, has been a serious public health issue in the Asia-Pacific region, with rising incidence and sporadic outbreaks.
Na-Young Ha   +8 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Antibody-guided identification of Achromobacter xylosoxidans protein antigens in cystic fibrosis

open access: yesmSphere
Persistent bacterial airway infection is a hallmark feature of cystic fibrosis (CF). Achromobacter spp. are gram-negative rods that can cause persistent airway infection in people with CF (pwCF), but the knowledge of host immune responses to these ...
Cecilia Sahl   +3 more
doaj   +1 more source

Crossroads between bacterial and mammalian glycosyltransferases

open access: yesFrontiers in Immunology, 2014
Bacterial glycosyltransferases often synthesize the same glycan linkages as mammalian glycosyltransferases, yet they usually have very little sequence identity.
Inka eBrockhausen
doaj   +1 more source

STUDIES ON THE ANTIGENIC SUBSTANCE OF THE BACTERIAL CELL [PDF]

open access: yesJournal of Experimental Medicine, 1925
Putting together the results of such experiments as those outlined above, we can set down the following definite facts. 1. The substance of the bacterial cell can be roughly divided into two antigenic entities. One of these is the so called "nucleoprotein" substance, the other the residue substance or soluble material of Dochez and Avery
H, Zinsser, T, Tamiya
openaire   +2 more sources

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