Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]
, 2015 O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi +8 more
core +1 more source
Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine against Staphylococcus aureus in a Rat Model of Osteomyelitis [PDF]
, 2014 Staphylococcus aureus is an invasive bacterial pathogen, and antibiotic resistance has impeded adequate control of infections caused by this microbe. Moreover, efforts to prevent human infections with single-component S. aureus vaccines have failed.
Buzzola, Fernanda Roxana +6 more
core +2 more sources
Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]
, 2017 Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L +6 more
core +2 more sources
Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model. [PDF]
PLoS ONE, 2014 Pertussis is a highly infectious respiratory disease of humans caused by the bacterium Bordetella pertussis. Despite high vaccination coverage, pertussis has re-emerged globally.
Daan de Gouw +9 more
doaj +1 more source
Outer membrane vesicles: A bacterial-derived vaccination system
Frontiers in Microbiology, 2022 Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj +1 more source
Emerging Microbes and Infections, 2020 Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes +10 more
doaj +1 more source
Frontiers in Immunology, 2022 Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical settings due to the emergence of antibiotic resistant strains and the lack of effective therapeutics.
Somshukla Chaudhuri +6 more
doaj +1 more source
Neutrophil and lymphocyte responses to oral Streptococcus in Adamantiades-Behcet's disease [PDF]
, 2005 Immune reactions against microorganisms play an important pathogenic role in Adamantiades-Behçet’s disease (ABD). We had previously obtained Streptococcus sanguinis (strain BD113-20) isolated from the oral cavity of patients with ABD.
Aoki +30 more
core +1 more source
Molecular cloning and expression of novel fibroblast growth factor-2 conjugated with immunodominant domains of pseudomonas exotoxin [PDF]
, 2015 Angiogenesis is very important in cancer growth and metastasis. Basic fibroblast growth factor (bFGF) as one of the most important angiogenesis factors is an attractive target for cancer vaccine.
Farazmandfar, T. +6 more
core +1 more source
Shared Antigens Between Heterologous Bacterial Species [PDF]
Infection and Immunity, 1972 Sera from normal rabbits were shown to have antibodies that bound radiolabeled test antigens derived from many taxonomically unrelated bacteria. Sera from rabbits that had been immunized with sonically treated material of 12 different bacteria, including M.
P, Minden, J K, McClatchy, R S, Farr
openaire +2 more sources