Results 81 to 90 of about 320,891 (294)

Leaf-Encapsulated Vaccines: Agroinfiltration and Transient Expression of the Antigen Staphylococcal Endotoxin B in Radish Leaves. [PDF]

, 2018
Transgene introgression is a major concern associated with transgenic plant-based vaccines. Agroinfiltration can be used to selectively transform nonreproductive organs and avoid introgression.
Gallo, Richard L, Huang, Chun-Ming, Liu, Pei-Feng, Simmons, Christopher W, Ulrich, Robert G, VanderGheynst, Jean S, Wang, Yanhan   +6 more
core   +3 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Salmonella modulates B cell biology to evade CD8+ T cell-mediated immune responses

Frontiers in Immunology, 2014
Although B cells and antibodies are the central effectors of humoral immunity, B cells can also produce and secrete cytokines and present antigen to helper T cells.
Marcela eLopez-Medina, Araceli ePerez-Lopez, Araceli ePerez-Lopez, Celia eAlpuche-Aranda, Vianney eOrtiz-Navarrete   +4 more
doaj   +1 more source

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., Balbao, J., Cabrera, O., Cuello, M., del Campo, J., Ferro, Valerie A., Gonzales, E., Romeu, B., Zayas, C.   +8 more
core  

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

FEATURES OF IMMUNE RESPONSE DURING VARIOUS SCHEMES OF USE OF BACTERIAL THERAPEUTIC VACCINE IMMUNOVAC VP-4

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Study the dynamics of immunologic parameters in patients with chronic bacterial infections during various schemes of administration of Immunovac VP-4 vaccine. Materials and methods.
L. I. Krasnoproshina, T. A. Serova, E. P. Foshina, I. V. Bisheva, S. A. Skhodova   +4 more
doaj   +1 more source

Protective vaccination in the horse against _Streptococcus equi_ with recombinant antigens [PDF]

, 2009
_Streptococcus equi_ subspecies _equi_ (_S. equi_) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, more commonly known as Strangles.
Andrew Waller, Bengt Guss, Carl Robinson, Jan-Ingmar Flock, Ken Smith, Lars Frykberg, Margareta Flock   +6 more
core   +1 more source

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
AD Reynolds, AM Faria, C Jokinen, C Laine, C O'Mahony, Carlos Javier Orihuela, D Bogaert, DM Musher, EJ Novak, EK Mulholland, EM Laughlin, G Oldenhove, H Christensen, HM Foy, HW Lim, I Rudan, JC Paton, Jeffrey Pido-Lopez, JL Round, JN Stoop, K Wing, KA Robinson, L Strauss, L Weiss, M Hara, M Hussain, M Lipsitch, M Livingston, M Quigley, MJ Butte, MJ van Kempen, MW Mureithi, N Iikuni, Neil A. Williams, PC Hill, PR Myles, Q Zhang, Q Zhang, Q Zhang, R Austrian, R Malley, R Malley, RM Wong, Robert S. Heyderman, S Hori, S Paust, S Rapola, S Read, S Sakaguchi, S Sakaguchi, SE Sandner, SK Obaro, SQ Crome, T Sturniolo, T Takahashi, Timothy J. Mitchell, V Davenport, William W. Kwok, X Zhang, Y Belkaid, Y Cong, YJ Lu, Z Zhang   +62 more
core   +3 more sources

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow, Nicola McKern, Vincent Oxenham, Kate Ahmad, Omar Ahmad   +4 more
wiley   +1 more source

Outer membrane vesicles (OMVs) and their therapeutic potential as anti-infectious agents

Nano Trends
Outer membrane vesicles (OMVs) derived from Gram-negative bacteria have emerged as promising therapeutic agents for combating infectious diseases. These small, spherical structures carry diverse cargo molecules, including virulence factors, antigens, and
Mariana Ottaiano Gonçalves, Paula Maria Pincela Lins, Giulia Kassab, Vanderlei Bagnato, Valtencir Zucolotto   +4 more
doaj   +1 more source