Results 81 to 90 of about 5,310 (124)

Preoperative sarcopenia negatively impacts short‐ and long‐term outcomes of rectal cancer: A propensity score‐matched analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study examined the effects of skeletal muscle mass on the short‐ and long‐term outcomes of rectal cancer. This study revealed that preoperative sarcopenia was associated with more total postoperative complications, more anastomotic leakage, and worse survival in rectal cancer patients.
Shinya Abe   +9 more
wiley   +1 more source

IL‐4/IL‐13‐producing ILC2s are required for timely control of intestinal helminth infection in mice

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1925-1933, December 2022., 2022
ILC2‐derived IL‐4/IL‐13 plays a non‐redundant role for eosinophil recruitment to the lung and expulsion of N. brasiliensis worm parasites from the intestine. Abstract Infection of mice with Nippostrongylus brasiliensis (Nb) serves as a model for human hookworm infection affecting about 600 million people world‐wide.
Filipa Varela   +4 more
wiley   +1 more source

Recent advances and challenges in temperature monitoring and control in microfluidic devices

open access: yesELECTROPHORESIS, Volume 44, Issue 1-2, Page 268-297, January 2023., 2023
Abstract Temperature is a critical—yet sometimes overlooked—parameter in microfluidics. Microfluidic devices can experience heating inside their channels during operation due to underlying physicochemical phenomena occurring therein. Such heating, whether required or not, must be monitored to ensure adequate device operation.
Alejandro A. Dos‐Reis‐Delgado   +6 more
wiley   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

An electrochemical comparison of thiolated self‐assembled monolayer (SAM) formation and stability in solution on macro‐ and nanoelectrodes

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract Thiolated self‐assembled monolayers (SAMs) formed on metal electrodes have been a topic of interest for many decades. One of the most common applications is in the field of biosensors, where this is a growing need for functionalizing nanoelectrodes to realize more sensitive and implantable sensors.
Andrew Piper   +2 more
wiley   +1 more source

Fluorescence Color Gradient Immunochromatographic Assay for Highly‐Sensitive, Quantitative, and Simultaneous Detection of Small‐Molecule Pollutants

open access: yesAggregate, EarlyView.
This article reports on a universal fluorescence color gradient immunochromatographic assay (FCGICA) technology based on the superposition of red and green fluorescence dual signals, which enables ultra‐sensitive, wide‐range, and simultaneous quantitative detection of multiple small molecules in complex samples.
Shu Wang   +8 more
wiley   +1 more source

Functional activity of peptide ion channels in tethered bilayer lipid membranes: Review

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract Ion transport across biomembranes plays a major role in living cells. This fundamental function is normally carried out by molecules with both a hydrophobic and a hydrophilic side (amphiphilic molecules), which aggregate within the membrane forming a hydrophilic pore (the ion channel) permitting the selective translocation of permeant ions ...
Rolando Guidelli, Lucia Becucci
wiley   +1 more source

Multifunctional Ultra‐Bright Plasmonic Gold@Fluorescence Nanoprobe for Biomedical Applications

open access: yesAggregate, EarlyView.
Plasmonic gold nanoparticles (AuNPs) with intrinsic superiorities in metal‐enhanced fluorescence (MEF) have been widely utilized in amplifying signal enhancement, fluorescent labeling, and theranostics. This review systematically discusses plasmonic AuNPs‐driven MEFs, from their enhancement mechanisms, influencing factors, and enhanced types, to their ...
Caiping Ding   +4 more
wiley   +1 more source

Dual‐gate ion‐sensitive field‐effect transistors: A review

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract Ion‐sensitive field‐effect transistors (ISFETs) are electrochemical sensors that work on the principle of metal‐oxide field‐effect transistors. Dual‐gate ion‐sensitive field‐effect transistors (DGISFETs) are an advanced version of ISFETs with an additional gate dielectric, resulting in sensitivity enhancement on account of the coupling of the
Deepa Bhatt, Siddhartha Panda
wiley   +1 more source

TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah   +2 more
wiley   +1 more source

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