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Diagnostic Potential of CD34+ Cell Antigen Expression in Myelodysplastic Syndromes [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2012
The World Health Organization introduced flow cytometry as an additional criterion for diagnosis of myelodysplastic syndromes (MDS). Aberrant antigen expression on bone marrow (BM) blasts may identify "low-grade MDS." This study aimed to examine differences in antigen expression on CD34+ BM cells between patients with MDS and those with secondary ...
De Smet, Dieter   +9 more
openaire   +5 more sources

Monoclonal antibodies against human CD34 antigens do not cross-react with ovine umbilical cord blood cells [PDF]

open access: yesItalian Journal of Animal Science, 2010
CD34 is a cell surface glycoprotein expressed by hematopoietic progenitors and endothelial cells. It is widely used in the clinic for isolation of human hematopoietic stem cells.
Maria Dattena   +4 more
doaj   +5 more sources

Generation of Novel Monoclonal Antibodies Recognizing Rabbit CD34 Antigen. [PDF]

open access: yesBiomolecules
The rabbit is a widely used experimental model for human translational research and stem cell therapy. Many studies have focused on rabbit mesenchymal stem cells from different biological sources for their possible application in regenerative medicine.
Vašíček J   +9 more
europepmc   +3 more sources

Juvenile myelomonocytic leukemia stem cells are sensitive to NK cell–mediated lysis and express targetable antigens [PDF]

open access: yesBlood Neoplasia
: Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm for which hematopoietic stem cell transplantation is the only curative treatment.
Shannalee Martinez   +9 more
doaj   +2 more sources

Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome [PDF]

open access: yes, 2017
Background: High-density lipoproteins (HDL) favorably affect endothelial progenitor cells (EPC). Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS).
Alam, Mohammad Afaque   +15 more
core   +24 more sources

CD117 expression on blast cells in acute myeloid leukemia [PDF]

open access: yesMedičnì Perspektivi, 2015
The aim of the present work was to analyze the frequency of CD117 (c-KIT) antigen expression on the blast cells in acute myeloid leukemia (AML), evaluation of the presence of the relationship between the expression of the c-KIT and leukemia according to ...
Goryainova N.V.   +2 more
doaj   +3 more sources

Characterisation of canine CD34+/CD45 diminished cells by colony-forming unit assay and transcriptome analysis

open access: yesFrontiers in Veterinary Science, 2022
Haematopoietic stem and progenitor cells (HSPCs) are used for transplantation to reconstruct the haematopoietic pathways in humans receiving severe chemotherapy.
Taro Ayabe   +9 more
doaj   +1 more source

A review of TSHR- and IGF-1R-related pathogenesis and treatment of Graves’ orbitopathy

open access: yesFrontiers in Immunology, 2023
Graves’ orbitopathy (GO) is an organ-specific autoimmune disease, but its pathogenesis remains unclear. There are few review articles on GO research from the perspective of target cells and target antigens.
Xuejiao Cui, Futao Wang, Cong Liu
doaj   +1 more source

Can CD34+CD38− lymphoblasts, as likely leukemia stem cells, be a prognostic factor in B-cell precursor acute lymphoblastic leukemia in children?

open access: yesFrontiers in Pediatrics, 2023
BackgroundCD34+CD38− lymphoblasts as likely leukemia stem cells (LSCs) may be responsible for a worse response to treatment and may be a risk factor for recurrence in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).ObjectiveThe study objective ...
Weronika Stolpa   +4 more
doaj   +1 more source

Alginate-Chitosan Microencapsulated Cells for Improving CD34+ Progenitor Maintenance and Expansion

open access: yesApplied Sciences, 2021
Protocols for isolation, characterization, and transplantation of hematopoietic stem cells (HSCs) have been well established. However, difficulty in finding human leucocyte antigens (HLA)-matched donors and scarcity of HSCs are still the major obstacles ...
Retno Wahyu Nurhayati   +6 more
doaj   +1 more source

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