Diagnostic Potential of CD34+ Cell Antigen Expression in Myelodysplastic Syndromes [PDF]
The World Health Organization introduced flow cytometry as an additional criterion for diagnosis of myelodysplastic syndromes (MDS). Aberrant antigen expression on bone marrow (BM) blasts may identify "low-grade MDS." This study aimed to examine differences in antigen expression on CD34+ BM cells between patients with MDS and those with secondary ...
De Smet, Dieter +9 more
openaire +5 more sources
Monoclonal antibodies against human CD34 antigens do not cross-react with ovine umbilical cord blood cells [PDF]
CD34 is a cell surface glycoprotein expressed by hematopoietic progenitors and endothelial cells. It is widely used in the clinic for isolation of human hematopoietic stem cells.
Maria Dattena +4 more
doaj +5 more sources
Generation of Novel Monoclonal Antibodies Recognizing Rabbit CD34 Antigen. [PDF]
The rabbit is a widely used experimental model for human translational research and stem cell therapy. Many studies have focused on rabbit mesenchymal stem cells from different biological sources for their possible application in regenerative medicine.
Vašíček J +9 more
europepmc +3 more sources
Juvenile myelomonocytic leukemia stem cells are sensitive to NK cell–mediated lysis and express targetable antigens [PDF]
: Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm for which hematopoietic stem cell transplantation is the only curative treatment.
Shannalee Martinez +9 more
doaj +2 more sources
Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome [PDF]
Background: High-density lipoproteins (HDL) favorably affect endothelial progenitor cells (EPC). Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS).
Alam, Mohammad Afaque +15 more
core +24 more sources
CD117 expression on blast cells in acute myeloid leukemia [PDF]
The aim of the present work was to analyze the frequency of CD117 (c-KIT) antigen expression on the blast cells in acute myeloid leukemia (AML), evaluation of the presence of the relationship between the expression of the c-KIT and leukemia according to ...
Goryainova N.V. +2 more
doaj +3 more sources
Haematopoietic stem and progenitor cells (HSPCs) are used for transplantation to reconstruct the haematopoietic pathways in humans receiving severe chemotherapy.
Taro Ayabe +9 more
doaj +1 more source
A review of TSHR- and IGF-1R-related pathogenesis and treatment of Graves’ orbitopathy
Graves’ orbitopathy (GO) is an organ-specific autoimmune disease, but its pathogenesis remains unclear. There are few review articles on GO research from the perspective of target cells and target antigens.
Xuejiao Cui, Futao Wang, Cong Liu
doaj +1 more source
BackgroundCD34+CD38− lymphoblasts as likely leukemia stem cells (LSCs) may be responsible for a worse response to treatment and may be a risk factor for recurrence in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).ObjectiveThe study objective ...
Weronika Stolpa +4 more
doaj +1 more source
Alginate-Chitosan Microencapsulated Cells for Improving CD34+ Progenitor Maintenance and Expansion
Protocols for isolation, characterization, and transplantation of hematopoietic stem cells (HSCs) have been well established. However, difficulty in finding human leucocyte antigens (HLA)-matched donors and scarcity of HSCs are still the major obstacles ...
Retno Wahyu Nurhayati +6 more
doaj +1 more source

