Results 1 to 10 of about 39,027 (253)

Characterisation of canine CD34+/CD45 diminished cells by colony-forming unit assay and transcriptome analysis

open access: yesFrontiers in Veterinary Science, 2022
Haematopoietic stem and progenitor cells (HSPCs) are used for transplantation to reconstruct the haematopoietic pathways in humans receiving severe chemotherapy.
Taro Ayabe   +9 more
doaj   +1 more source

CD117 expression on blast cells in acute myeloid leukemia. [PDF]

open access: yesMedičnì Perspektivi, 2015
The aim of the present work was to analyze the frequency of CD117 (c-KIT) antigen expression on the blast cells in acute myeloid leukemia (AML), evaluation of the presence of the relationship between the expression of the c-KIT and leukemia according to ...
N. V. Goryainova   +2 more
doaj   +2 more sources

A review of TSHR- and IGF-1R-related pathogenesis and treatment of Graves’ orbitopathy

open access: yesFrontiers in Immunology, 2023
Graves’ orbitopathy (GO) is an organ-specific autoimmune disease, but its pathogenesis remains unclear. There are few review articles on GO research from the perspective of target cells and target antigens.
Xuejiao Cui, Futao Wang, Cong Liu
doaj   +1 more source

Can CD34+CD38− lymphoblasts, as likely leukemia stem cells, be a prognostic factor in B-cell precursor acute lymphoblastic leukemia in children?

open access: yesFrontiers in Pediatrics, 2023
BackgroundCD34+CD38− lymphoblasts as likely leukemia stem cells (LSCs) may be responsible for a worse response to treatment and may be a risk factor for recurrence in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).ObjectiveThe study objective ...
Weronika Stolpa   +4 more
doaj   +1 more source

Alginate-Chitosan Microencapsulated Cells for Improving CD34+ Progenitor Maintenance and Expansion

open access: yesApplied Sciences, 2021
Protocols for isolation, characterization, and transplantation of hematopoietic stem cells (HSCs) have been well established. However, difficulty in finding human leucocyte antigens (HLA)-matched donors and scarcity of HSCs are still the major obstacles ...
Retno Wahyu Nurhayati   +6 more
doaj   +1 more source

GENERATION OF HUMAN MACROPHAGE EXPRESSING CHIMERIC ANTIGEN RECEPTORS DERIVED OF CD34+ CELLS FROM UMBILICAL CORD BLOOD FOR THE TREATMENT OF SOLID TUMORS

open access: yesHematology, Transfusion and Cell Therapy, 2023
Background: T lymphocytes expressing chimeric antigen receptors (CAR) have been shown to be efficient for tretment of hematologic, but less efficient for solid tumors, due to the great complexity of the tumor microenvironment involving: heterogeneity of ...
IC Ovider   +7 more
doaj   +1 more source

CD34 antigen: Molecular features and potential clinical applications [PDF]

open access: yesStem Cells, 1993
Despite the wide variety of functions exhibited by mature peripheral blood cells, all are derived from a small pool (1-3%) of primitive precursor cells in the bone marrow (BM) that bear a unique surface glycoprotein, CD34. Isolated CD34+ cells are capable of reconstituting all hematopoietic lineages, both in experimental animals and in humans following
D R, Sutherland   +2 more
openaire   +2 more sources

Diagnostic Potential of CD34+ Cell Antigen Expression in Myelodysplastic Syndromes [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2012
The World Health Organization introduced flow cytometry as an additional criterion for diagnosis of myelodysplastic syndromes (MDS). Aberrant antigen expression on bone marrow (BM) blasts may identify "low-grade MDS." This study aimed to examine differences in antigen expression on CD34+ BM cells between patients with MDS and those with secondary ...
De Smet, Dieter   +9 more
openaire   +4 more sources

CD34 antigen: Determination of specific sites of phosphorylation in vitro and in vivo [PDF]

open access: yesInternational Journal of Mass Spectrometry, 2011
CD34, a type I transmembrane glycoprotein, is a surface antigen which is expressed on several cell types, including hematopoietic progenitors, endothelial cells, as well as mast cells. Recently, CD34 has been described as a marker for epidermal stem cells in mouse hair follicles, and is expressed in outer root sheath cells of the human hair follicle ...
Leesa J, Deterding   +10 more
openaire   +2 more sources

IMMUNOPHENOTYPIC COMPARISON BETWEEN REACTIVE BONE MARROW B-LYMPHOCYTE PRECURSOR (HEMATOGONES) AND B-NEOPLASTIC LYMPHOBLAST LEUKAEMIA USING CD 34, CD 123 BY FLOWCYTOMETRY

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background:Flow cytometric study found that lymphoblasts of B acute lymphoblastic leukemia exhibited multiple aberrant antigens by which they can be distinguished from hematogones. These antigens are CD34 and CD123.
Yousra A. Shallan, Raad J. Musa
doaj   +4 more sources

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