Results 1 to 10 of about 39,027 (253)
Haematopoietic stem and progenitor cells (HSPCs) are used for transplantation to reconstruct the haematopoietic pathways in humans receiving severe chemotherapy.
Taro Ayabe +9 more
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CD117 expression on blast cells in acute myeloid leukemia. [PDF]
The aim of the present work was to analyze the frequency of CD117 (c-KIT) antigen expression on the blast cells in acute myeloid leukemia (AML), evaluation of the presence of the relationship between the expression of the c-KIT and leukemia according to ...
N. V. Goryainova +2 more
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A review of TSHR- and IGF-1R-related pathogenesis and treatment of Graves’ orbitopathy
Graves’ orbitopathy (GO) is an organ-specific autoimmune disease, but its pathogenesis remains unclear. There are few review articles on GO research from the perspective of target cells and target antigens.
Xuejiao Cui, Futao Wang, Cong Liu
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BackgroundCD34+CD38− lymphoblasts as likely leukemia stem cells (LSCs) may be responsible for a worse response to treatment and may be a risk factor for recurrence in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).ObjectiveThe study objective ...
Weronika Stolpa +4 more
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Alginate-Chitosan Microencapsulated Cells for Improving CD34+ Progenitor Maintenance and Expansion
Protocols for isolation, characterization, and transplantation of hematopoietic stem cells (HSCs) have been well established. However, difficulty in finding human leucocyte antigens (HLA)-matched donors and scarcity of HSCs are still the major obstacles ...
Retno Wahyu Nurhayati +6 more
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Background: T lymphocytes expressing chimeric antigen receptors (CAR) have been shown to be efficient for tretment of hematologic, but less efficient for solid tumors, due to the great complexity of the tumor microenvironment involving: heterogeneity of ...
IC Ovider +7 more
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CD34 antigen: Molecular features and potential clinical applications [PDF]
Despite the wide variety of functions exhibited by mature peripheral blood cells, all are derived from a small pool (1-3%) of primitive precursor cells in the bone marrow (BM) that bear a unique surface glycoprotein, CD34. Isolated CD34+ cells are capable of reconstituting all hematopoietic lineages, both in experimental animals and in humans following
D R, Sutherland +2 more
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Diagnostic Potential of CD34+ Cell Antigen Expression in Myelodysplastic Syndromes [PDF]
The World Health Organization introduced flow cytometry as an additional criterion for diagnosis of myelodysplastic syndromes (MDS). Aberrant antigen expression on bone marrow (BM) blasts may identify "low-grade MDS." This study aimed to examine differences in antigen expression on CD34+ BM cells between patients with MDS and those with secondary ...
De Smet, Dieter +9 more
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CD34 antigen: Determination of specific sites of phosphorylation in vitro and in vivo [PDF]
CD34, a type I transmembrane glycoprotein, is a surface antigen which is expressed on several cell types, including hematopoietic progenitors, endothelial cells, as well as mast cells. Recently, CD34 has been described as a marker for epidermal stem cells in mouse hair follicles, and is expressed in outer root sheath cells of the human hair follicle ...
Leesa J, Deterding +10 more
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Background:Flow cytometric study found that lymphoblasts of B acute lymphoblastic leukemia exhibited multiple aberrant antigens by which they can be distinguished from hematogones. These antigens are CD34 and CD123.
Yousra A. Shallan, Raad J. Musa
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