Results 1 to 10 of about 58,626 (275)

Monoclonal antibodies against human CD34 antigens do not cross-react with ovine umbilical cord blood cells [PDF]

open access: yesItalian Journal of Animal Science, 2010
CD34 is a cell surface glycoprotein expressed by hematopoietic progenitors and endothelial cells. It is widely used in the clinic for isolation of human hematopoietic stem cells.
Maria Dattena   +4 more
doaj   +5 more sources

Characterisation of canine CD34+/CD45 diminished cells by colony-forming unit assay and transcriptome analysis

open access: yesFrontiers in Veterinary Science, 2022
Haematopoietic stem and progenitor cells (HSPCs) are used for transplantation to reconstruct the haematopoietic pathways in humans receiving severe chemotherapy.
Taro Ayabe   +9 more
doaj   +1 more source

CD117 expression on blast cells in acute myeloid leukemia. [PDF]

open access: yesMedičnì Perspektivi, 2015
The aim of the present work was to analyze the frequency of CD117 (c-KIT) antigen expression on the blast cells in acute myeloid leukemia (AML), evaluation of the presence of the relationship between the expression of the c-KIT and leukemia according to ...
N. V. Goryainova   +2 more
doaj   +2 more sources

Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome [PDF]

open access: yes, 2017
Background: High-density lipoproteins (HDL) favorably affect endothelial progenitor cells (EPC). Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS).
Alam, Mohammad Afaque   +15 more
core   +17 more sources

A review of TSHR- and IGF-1R-related pathogenesis and treatment of Graves’ orbitopathy

open access: yesFrontiers in Immunology, 2023
Graves’ orbitopathy (GO) is an organ-specific autoimmune disease, but its pathogenesis remains unclear. There are few review articles on GO research from the perspective of target cells and target antigens.
Xuejiao Cui, Futao Wang, Cong Liu
doaj   +1 more source

Can CD34+CD38− lymphoblasts, as likely leukemia stem cells, be a prognostic factor in B-cell precursor acute lymphoblastic leukemia in children?

open access: yesFrontiers in Pediatrics, 2023
BackgroundCD34+CD38− lymphoblasts as likely leukemia stem cells (LSCs) may be responsible for a worse response to treatment and may be a risk factor for recurrence in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).ObjectiveThe study objective ...
Weronika Stolpa   +4 more
doaj   +1 more source

Alginate-Chitosan Microencapsulated Cells for Improving CD34+ Progenitor Maintenance and Expansion

open access: yesApplied Sciences, 2021
Protocols for isolation, characterization, and transplantation of hematopoietic stem cells (HSCs) have been well established. However, difficulty in finding human leucocyte antigens (HLA)-matched donors and scarcity of HSCs are still the major obstacles ...
Retno Wahyu Nurhayati   +6 more
doaj   +1 more source

CD34 antigen: Molecular features and potential clinical applications [PDF]

open access: yesStem Cells, 1993
Despite the wide variety of functions exhibited by mature peripheral blood cells, all are derived from a small pool (1-3%) of primitive precursor cells in the bone marrow (BM) that bear a unique surface glycoprotein, CD34. Isolated CD34+ cells are capable of reconstituting all hematopoietic lineages, both in experimental animals and in humans following
D R, Sutherland   +2 more
openaire   +2 more sources

GENERATION OF HUMAN MACROPHAGE EXPRESSING CHIMERIC ANTIGEN RECEPTORS DERIVED OF CD34+ CELLS FROM UMBILICAL CORD BLOOD FOR THE TREATMENT OF SOLID TUMORS

open access: yesHematology, Transfusion and Cell Therapy, 2023
Background: T lymphocytes expressing chimeric antigen receptors (CAR) have been shown to be efficient for tretment of hematologic, but less efficient for solid tumors, due to the great complexity of the tumor microenvironment involving: heterogeneity of ...
IC Ovider   +7 more
doaj   +1 more source

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase [PDF]

open access: yes, 2020
Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs.
Bausenwein, Judith   +13 more
core   +2 more sources

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