Results 171 to 180 of about 39,027 (253)

Contribution of Cardiac CD34⁺ Stromal Cells to Post-Myocardial Infarction Repair in Middle-Aged Rats. [PDF]

J Histochem Cytochem
Schneider DT, Dedkov EI.
europepmc   +1 more source

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

Aging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing, Jingjing Su, Yanjun Lin, Nengwen Huang, Sihui Zhang, Yuwei Zhou, Jie Lu, Weiping Chen, Kaixun He, Wenxiu Yuan, Yang Li, Geyuan Zheng, Pengyuan Hu, Dong Wu, Yanjing Ou, Jiang Chen   +15 more
wiley   +1 more source

Next-generation CAR-T therapy for acute myeloid leukemia: bridging innovation with clinical translation. [PDF]

Ann Hematol
Zhao X, Ming X, Wu J, Zhu X, Xiao Y.
europepmc   +1 more source

CD34-positive circulating cells quantification during follow-up in myeloproliferative neoplasms. [PDF]

Ann Hematol
Demoy M, Bauvais M, Vely A, Nicol T, Riou J, Le Jeanne H, Bauduin A, Rambaud H, Boyer F, Geneviève F, Boussaroque A, Copin MC, Ugo V, Orvain C, Luque Paz D.   +14 more
europepmc   +1 more source

Myeloid Cell Function and Cytokine Profiles in Paediatric Haemophilia A: Insights From FVIII and Emicizumab Prophylaxis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Haemophilia A (HA) is an X‐linked bleeding disorder caused by factor VIII (FVIII) deficiency, treated with FVIII infusions or, more recently, Emicizumab subcutaneously. Although Emicizumab is safe and effective, FVIII is still required for severe bleeding, trauma, or surgery, and few studies have compared these prophylactic options in ...
Alessia Cottonaro, Saicharan Akula, Berardino Pollio, Irene Ricca, Tiziano Martini, Roberto Albiani, Jacopo Agnelli Giacchello, Patrizia Sciancalepore, Roberto Santi, Antonia Follenzi, Simone Merlin   +10 more
wiley   +1 more source

Circulating Progenitor Cells, Regenerative Capacity and Cognition: Evidence From 2 Community-Based Cohorts. [PDF]

Arterioscler Thromb Vasc Biol
Ahmed T, Gold M, Kulshreshtha A, Woods E, Rahbar A, Hossain M, Ko YA, Medina-Inojosa J, Harris KA, Huang J, Maisuradze N, Owais M, Sakr SM, Thomas T, Goldstein F, Lah J, Waller E, Calhoun V, Quyyumi A, Hajjar I.   +19 more
europepmc   +1 more source

From Theory to Practice: Which Biomarkers Are Ready for Predicting Response in Advanced HCC?

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Systemic therapies for advanced hepatocellular carcinoma (HCC) have expanded considerably with the advent of tyrosine kinase inhibitors, immune checkpoint inhibitors and immunotherapy–anti‐angiogenic combinations. However, despite this therapeutic diversification, first‐line treatment selection remains largely empirical, as few biomarkers are ...
Marie Decraecker, Jean‐Frédéric Blanc, Samuel Amintas, Grégoire Manaud   +3 more
wiley   +1 more source

Dual epitope anti-LILRB4 synthetic T-cell receptor and antigen receptor (STAR)-T-cell therapy for relapsed/refractory acute myeloid leukemia. [PDF]

Signal Transduct Target Ther
Lv M, Zheng H, Pei X, Lei L, Chen W, Bao Y, Ding Y, Xu Z, Hu L, Wan Z, Zhao X, Zhou Z, Lin X, Huang X, Wang J, Zhao X.   +15 more
europepmc   +1 more source

Mediastinal Lymphoma in 70 Dogs Treated With Lomustine or Anthracycline‐Based Multi‐Agent Chemotherapy

Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 382-392, June 2026.
ABSTRACT Primary mediastinal lymphoma is rare in dogs and literature exploring this disease is limited. Therefore, the aim of this study was to describe presentation, treatment and outcome in a large cohort of dogs with mediastinal lymphoma and explore prognostic factors including chemotherapy protocol. This retrospective multi‐institute study included
Diogo Machado, Jose Alvarez Picornell, Isabel Amores‐Fuster, Sarah Benjamin, Thomas Kearns, Alenka Lavra Zajc, Yike Bing, Katie A. McNaught, Maria Sava, Charlotte Johnston, Beth Rolf, Andrew D. Yale   +11 more
wiley   +1 more source

Emerging strategies in CAR-T cell therapy for acute myeloid leukemia: overcoming heterogeneity and improving safety through dual-antigen targeting. [PDF]

Exp Hematol Oncol
Ocaña-Cara Á, Mutis T, van der Schans JJ.   +2 more
europepmc   +1 more source