Refined detection of CD34⁺CD38⁻CD45RA⁺ leukemic stem cells using a single-tube flow cytometry assay and its strong association with measurable residual disease in acute myeloid leukemia: a retrospective cohort study. [PDF]
Navidinia AA +11 more
europepmc +1 more source
Abstract Background Vitamin C (VitC) is a cofactor for TET enzymes involved in DNA demethylation and epigenetic regulation. Mutations in TET2 are common drivers of leukemia. Preclinical studies suggest that VitC may delay leukemia progression. This study aimed to evaluate the biological activity, safety, and clinical impact of oral VitC in patients ...
Stine Ulrik Mikkelsen +26 more
wiley +1 more source
Role of Flow Cytometric Enumeration of Circulating hMICL (CD371) Positive Leukemic Stem Cells in Diagnosis and Prognostication of BCR::ABL1-Negative Myeloproliferative Neoplasms. [PDF]
Oberoi G +10 more
europepmc +1 more source
Synovial fluid contains heterogeneous EV populations reflecting stromal and immune‐associated cellular inputs from the arthritic joint. SEC‐UF enrichment coupled to CD90‐targeted immunocapture enables recovery of stromal‐associated EV subpopulation from complex patient synovial fluid, while focused LC‐MS/MS and cell‐of‐origin analysis enable molecular ...
Stefanie Kurth +12 more
wiley +1 more source
Maintenance of Hokkaido virus, a genotype of <i>Orthohantavirus puumalaense</i>, in the rodent host <i>Myodes rufocanus bedfordiae</i> under natural conditions. [PDF]
Duong TNT +9 more
europepmc +1 more source
Ex vivo-generated conventional dendritic cells type 1 and type 2 from blood progenitors induce potent antigen-specific T-cell immunity. [PDF]
Cuenca-Escalona J +6 more
europepmc +1 more source
Linking HLA class II susceptibility to HSPC transcriptomics and antigen presentation in aplastic anemia. [PDF]
Correa Lara M +2 more
europepmc +1 more source
ABSTRACT Umbilical cord blood transplantation is a viable source of stem cells due to accessibility and low incidence of chronic graft‐versus‐host disease despite human‐leukocyte‐antigen mismatching. Disadvantages of low stem cell dose in larger recipients include delayed immune reconstitution, graft rejection, and mortality.
Rachel E. Granberg +4 more
wiley +1 more source
Applications of humanized mice in <i>Mycobacterium tuberculosis</i> infections (Review). [PDF]
Han B +5 more
europepmc +1 more source
ABSTRACT This study aimed to elucidate the cellular and molecular mechanisms underlying knee osteoarthritis pathogenesis by analyzing chondrocyte populations and their spatial distribution using single‐cell RNA sequencing (scRNA‐seq). Knee cartilage cells underwent scRNA‐seq.
Yu Kobori +19 more
wiley +1 more source

