The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma +6 more
wiley +1 more source
Steady-state mobilization with on-demand plerixafor after CD38 antibody-based induction in multiple myeloma patients. [PDF]
Röhnert MA +13 more
europepmc +1 more source
This study compared clinical outcomes and immune reconstitution in haplo‐HSCT patients receiving PTCY (n = 45), ATG (n = 45), or PTCY+ATG (n = 45). The ATG group had superior OS (p = 0.029) and LFS (p = 0.034), with higher CD3+ and CD8+ T‐cell counts at 3 months.
Xiao‐Di Ma +11 more
wiley +1 more source
Integrating flow cytometric profile and gene mutation analysis of intact lymph nodes to refine lymphoma immunophenotype. [PDF]
Peng QY +4 more
europepmc +1 more source
Integrative Proteogenomic Characterization of Left‐Sided and Right‐Sided Colorectal Cancer
This study performed whole‐exome sequencing, proteomic, and phosphoproteomic analysis on 80 pairs of tumor tissues and matched normal adjacent tissues from colorectal cancer patients. The integrated proteogenomic study provides a comprehensive and nuanced understanding of the molecular heterogeneity between left‐ and right‐sided colorectal cancer ...
An Huang +11 more
wiley +1 more source
Immunoreactivity for CD34, Desmin, Keratins, KIT, Alpha-Smooth Muscle Actin, S100, and Vimentin in Malignant Mesenchymal Neoplasms in Guinea Pigs: A Series of 62 Cases From a Single Institution. [PDF]
Lenz J, Škorič M, Tichý F, Fiala L.
europepmc +1 more source
Ribosomal Proteins in Cell Biology and Cancer
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang +4 more
wiley +1 more source
Clonal dynamics, tolerance, and adverse events after CD45-ADC-conditioned autologous HSPC transplantation in macaques. [PDF]
Hayal TB +22 more
europepmc +1 more source
Circulating Mononuclear Cells Expressing the CD34 Antigen in Aplastic Anemia.
KOBAYASHI, Ryoji +6 more
openaire +1 more source
ABSTRACT Objective We investigated the role of GLI3, a transcription factor highly expressed in the pathogenic THY1+CD34− sublining subset of rheumatoid arthritis synovial fibroblasts (RASFs), in regulating their pathogenic behavior. Methods GLI3 protein levels were quantified in freshly isolated RASF subsets by Western blotting.
Motohiko Sato +14 more
wiley +1 more source

