Results 211 to 220 of about 1,141,456 (326)

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

Efficacy of Repeated Administration of Cultured Human CD34⁺ Cells Against Streptozotocin-Induced Diabetic Nephropathy in Rats. [PDF]

Cells
Ohtake T, Salybekov AA, Sato T, Okamura S, Yazawa M, Yano Y, Hassanpour M, Yanai M, Imagawa M, Asahara T, Kobayashi S.   +10 more
europepmc   +1 more source

The generation of human natural killer cells from CD34+/DR- primitive progenitors in long-term bone marrow culture.

Blood, 1992
Jeffrey S. Miller, C. Verfaillie, P. Mcglave   +2 more
semanticscholar   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou, Zhenfei Zhong, Peng Hu, Weigang Wang, Ying Song, Na Yang, Fangyan He, Yajie Li, Qi Sa, Yanmei Yang, Qinmiao Sun, Tonghua Yang, Beibei Zhang, Dahua Chen   +13 more
wiley   +1 more source

Functional and molecular analyses reveal impaired HSPCs in Multiple Myeloma patients post-induction. [PDF]

Stem Cells Transl Med
Baumhardt TM, Amoah A, Hoenicka M, Liebold A, Sakk V, Soller K, Vollmer A, Kull M, Kronke J, Mallm JP, Geiger H, Mulaw M.   +11 more
europepmc   +1 more source

Bone Marrow Mesenchymal Stem Cell Hydrogel‐Mediated Fibroblast Reprogramming Restores Intestinal Function in Adhesive Small Bowel Obstruction

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Conceptual diagram and schematic illustration of microenvironmental changes in individuals with ASBO before and after treatment. BMSC@Gel therapy transforms the ASBO microenvironment from an inflammatory, fibrotic state with aberrant matrix deposition and barrier dysfunction to a regenerative state with reduced inflammation and improved structural ...
Lihong Zheng *, Junrong Zhang *, Zhengyuan Huang *, Zhenliang Lin, Jin Zhang, Da Zhang, Ping Hou, Xianqiang Chen   +7 more
wiley   +1 more source

Monocyte‐Derived Macrophages‐Synovial Fibroblasts Crosstalk Unravels Oncostatin Signaling Network as a Driver of Synovitis in Osteoarthritis

Arthritis &Rheumatology, Volume 78, Issue 1, Page 105-118, January 2026.
Objective Osteoarthritis (OA) is a debilitating joint disease that is characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Damien Laouteouet, Olivier Bortolotti, Léa Marineche, Nicole Hannemann, Manon Chambon, Yaël Glasson, Anne‐Sophie Dumé, Julien De Lima, Maud Fournial, Dylan Touchet, Dany Séverac, Felicia Leccia, Christophe Duperray, Henri‐Alexandre Michaud, Farida Djouad, Benoît Le Goff, Frédéric Blanchard, Florence Apparailly, Gabriel Courties   +18 more
wiley   +1 more source

Tissue-Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts. [PDF]

Am J Hematol
Valent P, Wojta J, Kovanen PT, Hermine O, Fend F, Sotlar K, Greinix H, Geissler K, Hartmann K, Schwaab J, Herling M, Boccuni L, Kazianka L, John MV, Sperr WR, Zierfuss C, Tzankov A, Sillaber C, Minkov M, Hoermann G, Collin M, Horny HP, Haferlach T, Sibilia M, Haroche J, La Rosée P, Orfao A, Arock M.   +27 more
europepmc   +1 more source

Femoral PEComa Treated With Combined Surgery and Radiotherapy: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor, and primary involvement of the bone is exceptionally uncommon. In this report, a case of malignant PEComa arising from the femur in an elderly patient is described.
Yanluqi He, Kaili Fu, Ling Xue, Yaohua Fan, Dongjuan Wu   +4 more
wiley   +1 more source

T Cell/Mast Cell Crosstalk in the Skin of Patients Suffering From Immune‐Mediated Diseases, Focusing on Chronic Spontaneous Urticaria

Clinical and Translational Allergy, Volume 16, Issue 1, January 2026.
ABSTRACT The crosstalk between immune cells in skin lesions of numerous immune‐mediated diseases such as atopic dermatitis, psoriasis and other T cell mediated is fundamental for understanding the pathogenesis and treating these diseases. The mechanisms by which most activated immune cells such as T cells, mast cells, and neutrophils are shifted from ...
Elias Toubi, Raeda Mubariki, Zahava Vadasz   +2 more
wiley   +1 more source