Results 41 to 50 of about 8,885 (125)
ABSTRACT Generalised Granuloma Annulare (GGA) is a chronic inflammatory skin disorder with no standard treatment. Since the last review in 2013, new treatments and varied responses have highlighted the need for an updated synthesis to guide clinical decisions.
Luca Bettolini +11 more
wiley +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications
RNA epigenetics regulates cancer through RNA modifications, splicing, transport, and translation. Key components include m⁶A writers, splicing factors, RBPs, and nuclear export machinery. Aberrant RNA metabolism drives tumor progression and immune evasion.
Shanhe Huang +4 more
wiley +1 more source
Lack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia. [PDF]
B cell chronic lymphocytic leukemia (CLL) is a malignancy of the CD5+ B cells. Prior studies indicated that CLL B cells generally express immunoglobulin (Ig) VH and VL genes with little or no somatic mutations.
Kipps, TJ, Rassenti, LZ
core
Trafficking properties of plasmacytoid dendritic cells in health and disease. [PDF]
Plasmacytoid dendritic cells (PDCs) represent a subset of circulating leukocytes characterized by the ability to release high levels of type I interferon (IFN). Under homeostatic conditions PDCs are confined to primary and secondary lymphoid organs. This
Del Prete A +3 more
core +1 more source
Dysregulation of of phospholipid-specific phagocytosis by B1 B cells in diet-induced obese mice [PDF]
B1 B cells have received increasing attention recently due to their newly discovered phagocytic and microbicidal capabilities. Several studies have demonstrated that B1 cells can phagocytize polystyrene fluorescent particles, bacteria (Staphylococcus ...
Vo, Hung
core +1 more source
Monoclonal antibodies specific for differentiation antigens of human myelomonocytic cells.
Several monoclonal antibodies specific for human cells of the myelomonocytic lineage at discrete stages of differentiation have been described. In this review I briefly summarize the results obtained with these reagents and discuss their possible use for the study of cell lineage and functional activities of normal peripheral blood leukocytes, for the ...
openaire +1 more source
Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, Volume 77, Issue 10, Page 1305-1316, October 2025.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Acute Promyelocytic Leukemia in Four Year Old Female Child - A Case Report [PDF]
Leukemia is the most common malignancy of childhood representing about 30 % of oncohematological diseases diagnosed in children less than 15 years of age.
Anirudha V. Kushtagi +3 more
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LABRAD : Vol 41, Issue 2 - July 2015 [PDF]
An Overview of Immunoglobulin G4-Related Disease Plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) a Marker of Acute Kidney Injury Celiac Disease: Biomarkers for Diagnosis and Monitoring Pathophysiology of Paroxysmal Nocturnal Haemoglobinuria and ...
Aga Khan Universiity Hospital, Karachi
core +1 more source

