Results 131 to 140 of about 3,143,934 (294)

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

mRNA Vaccines in Melanoma Immunotherapy-A Narrative Review. [PDF]

Cells
Plewa P, Ćmil M, Lewandowski F, Poniewierska-Baran A, Pawlik A.   +4 more
europepmc   +1 more source

Human macrophage maturation and heterogeneity: analysis with a newly generated set of monoclonal antibodies to differentiation antigens.

Blood, 1986
R. Andreesen, K. Bross, J. Osterholz, F. Emmrich   +3 more
semanticscholar   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Dendritic Cell Organization and Function in Innate and Adaptive Immune Defense Within Lymph Nodes. [PDF]

Immunol Rev
Huang JY, Gerner MY.
europepmc   +1 more source

Surface differentiation antigens of human mammary epithelial cells carried on the human milk fat globule.

Proceedings of the National Academy of Sciences of the United States of America, 1977
R. Ceriani, K. Thompson, J. Peterson, S. Abraham   +3 more
semanticscholar   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

The emerging role of dendritic cells in the tumor microenvironment: from antigen presentation to targeted immunotherapy. [PDF]

Cell Death Dis
Xie Z, Fang Y, Zhang X, Fang Y, Li R, Guo Y, Yang Y, Yang S, Song L.   +8 more
europepmc   +1 more source

Laser‐Microscribed Glass Enables Surface‐Microfluidics‐Facilitated, Affordable, Rapid Cancer Diagnosis

Advanced Functional Materials, EarlyView.
A transparent, laser‐microscribed glass platform enables cancer diagnosis within 1 h—much faster than histology, which takes days, and free from the chemical or contrast risks of MRI or CT scans. The antibody‐functionalized rough glass surface captures viable cancer cells directly from suspension, allowing instant optical readout and offering a rapid ...
Anish Pal, Snehasis Mishra, Arani Mukhopadhyay, Ilias Papailias, Atique U. Ahmed, Constantine M. Megaridis   +5 more
wiley   +1 more source

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A. [PDF]

Transbound Emerg Dis
Li D, Deng J, Wang Z, Zhang Y, Li Y, Hao L, Tian K, Li X.   +7 more
europepmc   +1 more source