Results 21 to 30 of about 3,143,934 (294)

HLA and immunodominance in viral infection: T-cell responses in protection and immunopathogenesis [PDF]

Microbiology Australia, 2021
The protective role of T cells in viral infection is well described. T cells generally mediate anti-viral immune responses via direct cytotoxicity and production of pro-inflammatory cytokines, by providing help to B cells and by promotion of memory ...
Suzi McCarthy, Allison Imrie
doaj  

Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets

Journal of Experimental Medicine, 1982
The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma.
A. Houghton, M. Eisinger, A. Albino, J. G. Gairncross, L. Old, M. Cholera Toxin ( Schwartz, Mann Div, Becton   +7 more
semanticscholar   +1 more source

Presensitization to Ascaris antigens promotes induction of mite-specific IgE upon mite antigen inhalation in mice

Allergology International, 2016
Background: Patients with house dust mite (HDM) allergy or Ascariasis produce serum IgE specific to the antigens of HDM or nematode Ascaris, respectively.
Mayu Suzuki, Mutsuko Hara, Saori Ichikawa, Seiji Kamijo, Takuya Nakazawa, Hideki Hatanaka, Kazuo Akiyama, Hideoki Ogawa, Ko Okumura, Toshiro Takai   +9 more
doaj   +1 more source

Differentiation between Mycobacterium bovis BCG-Vaccinated and M. bovis-Infected Cattle by Using Recombinant Mycobacterial Antigens

Clinical Diagnostic Laboratory Immunology, 1999
Tuberculosis continues to be a worldwide problem for both humans and animals. The development of tests to differentiate between infection with Mycobacterium tuberculosis orMycobacterium bovis and vaccination with M.
B. Buddle, N. Parlane, D. Keen, F. Aldwell, J. Pollock, K. Lightbody, P. Andersen   +6 more
semanticscholar   +1 more source

Establishment of competitive binding assay to detect and differentiate hepatitis E virus infection

Annals of Hepatology, 2019
Introduction and Objectives: This study was undertaken to demonstrate a promising approach for detection and differentiation the serum immunoglobulin G (IgG) against hepatitis E virus (anti-HEV IgG) using a competitive binding assay established with ...
Jiyue Wen, Weizhuo Lu, Jihong Meng
doaj   +1 more source

Human mononuclear phagocyte differentiation antigens. I. Patterns of antigenic expression on the surface of human monocytes and macrophages defined by monoclonal antibodies.

Journal of Immunology, 1983
Six newly developed monoclonal antibodies recognizing antigenic determinants expressed on the surface of human mononuclear phagocytes (MoPh) were applied to the antigenic analysis of this cell lineage.
A. Dimitriu-Bona, G. Burmester, S. Waters, R. Winchester   +3 more
semanticscholar   +1 more source

Mechanisms of autoantibody production in systemic lupus erythematosus

Frontiers in Immunology, 2015
Autoantibodies against a panoply of self-antigens are seen in SLE, but only a few (anti-Sm/RNP, anti-Ro/La, anti-dsDNA) are common. The common lupus autoantigens are nucleic-acid complexes and levels of autoantibodies can be extraordinarily high.
Shuhong eHan, Haoyang eZhuang, Stepan eShumyak, Lijun eYang, Westley H. Reeves   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source