Results 111 to 120 of about 195,323 (225)

Immunization with PIII, a fraction of Schistosoma mansoni soluble adult worm antigenic preparation, affects nitric oxide production by murine spleen cells

Memorias do Instituto Oswaldo Cruz, 1998
Nitric oxide (NO) is an important effector molecule involved in immune regulation and defense. NO produced by cytokine-activated macrophages was reported to be cytotoxic against the helminth Schistosoma mansoni.
Diana Magalhães de Oliveira, Silvânia Antunes do Carmo, David N Silva-Teixeira, Alfredo Miranda Goes   +3 more
doaj   +1 more source

Schistosoma mansoni Infection Can Jeopardize the Duration of Protective Levels of Antibody Responses to Immunizations against Hepatitis B and Tetanus Toxoid.

PLoS Neglected Tropical Diseases, 2016
BackgroundSchistosomiasis is a disease of major public health importance in sub-Saharan Africa. Immunoregulation begins early in schistosome infection and is characterized by hyporesponsiveness to parasite and bystander antigens, suggesting that a ...
Diana K Riner, Eric M Ndombi, Jennifer M Carter, Amos Omondi, Nupur Kittur, Emmy Kavere, Harrison K Korir, Briana Flaherty, Diana Karanja, Daniel G Colley   +9 more
doaj   +1 more source

Convergence between helminths and breast cancer: intratumoral injection of the excretory/secretory antigens of the human parasite Toxocara canis (EST) increase lung macro and micro metastasis

Frontiers in Immunology
IntroductionWorldwide, breast cancer is the most important cancer in incidence and prevalence in women. Different risk factors interact to increase the probability of developing it.
Raúl Aragón-Franco, Rocío Alejandra Ruiz-Manzano, Karen Elizabeth Nava-Castro, Víctor Hugo Del Rìo Araiza, Claudia Angelica Garay-Canales, Armando Pérez-Torres, Romel Chacón-Salinas, Manuel Iván Girón-Pérez, Jorge Morales-Montor   +8 more
doaj   +1 more source

Macrophage-derived extracellular vesicles from Ascaris lumbricoides antigen exposure enhance Mycobacterium tuberculosis growth control, reduce IL-1β, and contain miR-342-5p, miR-516b-5p, and miR-570-3p that regulate PI3K/AKT and MAPK signaling pathways

Frontiers in Immunology
BackgroundHelminth coinfection with tuberculosis (TB) can alter the phenotype and function of macrophages, which are the major host cells responsible for controlling Mycobacterium tuberculosis (Mtb).
Giggil Pushpamithran, Robert Blomgran
doaj   +1 more source

Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen.

PLoS Neglected Tropical Diseases
BackgroundThe exposure to parasites may influence the immune response to vaccines in endemic African countries. In this study, we aimed to assess the association between helminth exposure to the most prevalent parasitic infections, schistosomiasis, soil ...
Houreratou Barry, Edouard Lhomme, Mathieu Surénaud, Moumini Nouctara, Cynthia Robinson, Viki Bockstal, Innocent Valea, Serge Somda, Halidou Tinto, Nicolas Meda, Brian Greenwood, Rodolphe Thiébaut, Christine Lacabaratz   +12 more
doaj   +1 more source

T-cell migration: a naive paradigm?

, 2007
Naive T cells have long been thought to recirculate exclusively between secondary lymphoid organs via the lymph and blood. Evidence is now emerging that this view may be too simplistic and that naive T cells routinely traffic through non-lymphoid organs ...
Cose, SC, Stephen Cose, Cose, Stephen
core   +1 more source

Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathway.

, 2006
Only activated and effector memory T cells are thought to access non-lymphoid tissues. In contrast, naive T cells are thought to circulate only between the blood, lymph and secondary lymphoid organs.
Cose, SC, Khanna, KM, Masopust, David, David Masopust, Lefrançois, Leo, Clair Brammer, Stephen Cose, Masopust, D, Kamal M. Khanna, Brammer, C, Cose, Stephen, Khanna, Kamal M, Brammer, Clair, Leo Lefrançois, Lefrancois, L   +14 more
core   +1 more source

Modulation of the immune response by current and novel treatments for hepatitis C virus

Hepatitis C virus (HCV) infection is a major global healthcare problem infecting 180 million people worldwide. Infection persists in 80% of patients and is thought to result from a failure to sustain an immune response to HCV.
Barker, Sophie Joanna
core   +1 more source

Impact of Prior Exposure to Anisakis simplex Antigens on Immune Response During SARS-CoV-2 Vaccination. [PDF]

Parasite Immunol
Cuéllar C, Rodero M, González-Fernández J, Galindo-Regal L, López-Chuliá F, García-Ballesteros C, Fernández-Murga L, Llombart-Cussac A, Domínguez-Márquez MV, Andreu-Ballester JC.   +9 more
europepmc   +1 more source

Parasites and allergies: a complex bidirectional relationship from evolutionary origins to modern therapeutics. [PDF]

Antonie Van Leeuwenhoek
Packi K, Świerczewski D, Klimczak S, Ochab D, Gałęziewska J, Gromek P, Kruczkowska W, Płuciennik E, Kałuzińska-Kołat Ż, Kołat D.   +9 more
europepmc   +1 more source