Results 51 to 60 of about 1,276,188 (160)
The effects of symmetry on the dynamics of antigenic variation [PDF]
J. Math. Biol. 66, 115-137 (2013), 2012 In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in malaria, we show how many of the observed dynamical regimes can be explained in terms of the symmetry of ...
arxiv +1 more source
Advancements in Chimeric Antigen Receptor T Cell Therapy for Hepatocellular Carcinoma [PDF]
E3S Web of ConferencesChimeric antigen receptor T cell (CAR-T) therapy nowadays symbolizes an innovative paradigm of neoplasm immunotherapy that employs genetic engineering techniques to empower T cells and make it have a capability to precisely identify tumor-associated ...
Zhao Xinyu
doaj +1 more source
Dermatopathology, 2022 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare tumor that affects elderly individuals and presents a poor prognosis. Skin is the most common site of involvement, accounting for 89% of the cases.
Phanitchanat Phusuphitchayanan +6 more
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Mathematical models for order of mutation problem in myeloproliferative neoplasm: non-additivity and non-commutativity [PDF]
arXiv, 2023 In some patients of myeloproliferative neoplasm, two genetic mutations can be found: JAK2 V617F and TET2. When one mutation is present or not, the other mutation has different effects on regulating gene expressions. Besides, when both mutations are present, the order of occurrence might make a difference.
arxiv
Growth stage dependent expression of MHC antigens on the canine transmissible venereal sarcoma.
British Journal of Cancer, 1987 Canine transmissible venereal sarcoma (CTVS) is a naturally occurring contagious neoplasm which can be transplanted with intact viable cells across major histocompatibility (MHC) barriers within the species and even to other members of the canine family,
T. J. Yang, J. Chandler, S. Dunne-Anway
semanticscholar +1 more source
Frontiers in Medicine, 2022 A 74-year-old woman presented with a 30-day history of blisters and erosions in the oral cavity, trunk, and left eye conjunctival mucosa, also reporting a weight loss of 15 kg in the last 3 months.
Eleonora Quattri +9 more
doaj +1 more source
Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm [PDF]
arXiv, 2023 We develop a modeling framework for cancer progression that distinguishes the order of two possible mutations. Recent observations and information on myeloproliferative neoplasms are analyzed within our framework. In some patients with myeloproliferative neoplasms, two genetic mutations can be found, JAK2 V617F and TET2.
arxiv
Journal of Investigative Dermatology, 1992 The recognition and presentation of tumor-associated antigens by cutaneous antigen-presenting cells (APC) may play an important role in the establishment of effective defense mechanisms against newly emerging tumors in the skin.
Stephan Grabbe, S. Bruvers, R. Granstein
semanticscholar +1 more source
Immunoprofiling of Drosophila Hemocytes by Single-cell Mass Cytometry
Genomics, Proteomics & Bioinformatics, 2021 Single-cell mass cytometry (SCMC) combines features of traditional flow cytometry (i.e., fluorescence-activated cell sorting) with mass spectrometry, making it possible to measure several parameters at the single-cell level for a complex analysis of ...
József Á. Balog +6 more
doaj
Identifying the genetic basis of antigenic change in influenza A(H1N1) [PDF]
PLoS Pathogens (2016) 12(4): e1005526, 2014 Determining phenotype from genetic data is a fundamental challenge. Influenza A viruses undergo rapid antigenic drift and identification of emerging antigenic variants is critical to the vaccine selection process. Using former seasonal influenza A(H1N1) viruses, hemagglutinin sequence and corresponding antigenic data were analyzed in combination with 3-
arxiv +1 more source