Results 71 to 80 of about 1,314,756 (309)

Tumor-infiltrating lymphocytes and histocompatibility antigens in primary intracranial germinomas.

Journal of Neurosurgery, 1989
Subpopulations of tumor-infiltrating lymphocytes (TIL's) and the major histocompatibility complex (MHC) antigens of neoplastic cells were examined in three intracranial germinomas by an immunohistochemical method using monoclonal antibodies. About 70% to
T. Saito, R. Tanaka, Mituo Kouno, K. Washiyama, S. Abe, T. Kumanishi   +5 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

PET/CT imaging for tumour response assessment to immunotherapy: current status and future directions

European Radiology Experimental, 2020
Recent immunotherapeutic approaches have evolved as powerful treatment options with high anti-tumour responses involving the patient’s own immune system. Passive immunotherapy applies agents that enhance existing anti-tumour responses, such as antibodies
Marcus Unterrainer, Michael Ruzicka, Matthias P. Fabritius, Lena M. Mittlmeier, Michael Winkelmann, Johannes Rübenthaler, Matthias Brendel, Marion Subklewe, Michael von Bergwelt-Baildon, Jens Ricke, Wolfgang G. Kunz, Clemens C. Cyran   +11 more
doaj   +1 more source

EVALUATION OF BLOOD-GROUP-RELATED CARBOHYDRATE ANTIGENS IN THYROID NEOPLASMS

Nippon Jibiinkoka Gakkai Kaiho, 1995
An immunohistochemical study using a panel of monoclonal antibodies (mAbs) against blood group A, B, H and Lewis antigens Le(a), Le(b), Le(x) and Le(y) and lectins, such as PNA, VVA-B4 and UEA -1, was carried out to investigate the aberrant expression of carbohydrate antigens in formalin-fixed, paraffin-embedded tissue sections of thyroid neoplasms ...
Takashi Matsunaga, Masako Yokota, Nobuaki Ito, Katsunari Yane, Hiroshi Miyahara, Osamu Tanaka   +5 more
openaire   +4 more sources

Rearrangements of T-cell antigen receptor delta chain gene in hematologic neoplasms [PDF]

Blood, 1989
Rearrangements of the T-cell antigen receptor (TCR) delta chain gene were studied in primary neoplastic cells from 137 patients with leukemia or lymphoma. TCR delta gene rearrangements or deletions were observed in all 50 T-cell neoplasms: 5 of 8 CD3- T-cell neoplasms showed rearrangements, whereas biallelic deletion of TCR delta gene was the most ...
Fumio Kawano, Toshio Hattori, Masao Matsuoka, Norio Asou, Kiyoshi Takatsuki   +4 more
openaire   +3 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Radio Immuno Imaging and Therapy

Journal of Indian Academy of Oral Medicine and Radiology, 2006
Inherent in the application of advances in biomedical science to nuclear medicine is the concept of molecular targeting. Radioimmunoimaging and therapy can add a new dimension to diagnostic imaging and staging of head and neck cancer including metastasis,
P Raghu Obul Reddy, M C Shashikanth, I M Ali   +2 more
doaj  

Umbilico-placental antigens and malignant neoplasms.

The Bulletin of Tokyo Medical and Dental University, 1972
Serological reactions between anti-human placental tissue antiserum and 584 human sera from patients of various diseases and conditions have been tested using the micro-Ouchterlony method. Relatively high incidence of positive reaction was noted with cases of malignant tumours (57.5%), leukaemia (63.6%), pregnancy (77.8%), myocardial infarction (41.2%),
Wataru MORI, Hideo ASAKAWA
openaire   +1 more source

A reappraisal of the value of carcinoembryonic antigen in the management of patients with various neoplasms

Journal of British Surgery, 1979
Summary Eight hundred and eight patients with histologically proved malignant disease had carcinoembryonic antigen (CEA) estimations performed at the time of tissue diagnosis. An elevated level was found in 384 of 518 patients with gastrointestinal neoplasms (74 per cent) and in 162 of 290 patients with other neoplasms (56 per cent).
Colin R. Mackie, David B. Skinner, M J Cooper, A. R. Moossa   +3 more
openaire   +3 more sources