Results 71 to 80 of about 49,776 (318)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Follicular dendritic cell sarcoma with paraneoplatic pemphigus: Rare case and a brief review of literature

Indian Journal of Medical and Paediatric Oncology, 2013
Paraneoplastic pemphigus (PNP) is often a fatal autoimmune bullous disease characterized by severe stomatitis, polymorphous skin eruptions, and underlying neoplasms. We describe a patient with PNP associated with follicular dendritic cell sarcoma (FDCS),
Saphalta Baghmar, Sanjeev Kumar, S Dutta Gupta, Vinod Raina   +3 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Evaluation of the activity of the immune system and age-related tissue markers in Turquoise killifish \ud (Nothobranchius furzeri, Jubb 1971) \ud and their role in cell ageing\ud [PDF]

, 2010
Currently the Turquoise Killifish is considered the best animal model suitable for aging research. \ud This annual fish, from south east Africa, shows an exceptionally adaptive behaviour to dry periods: indeed, due to this extreme environmental ...
Di Cicco, Emiliano, Rossi, Giacomo
core  

Mathematical modeling to elucidate brain tumor abrogation by immunotherapy with T11 target structure

, 2015
T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the immune cells.
Banerjee, Sandip, Chowdhury, Swapna, Khajanchi, Subhas   +2 more
core   +2 more sources

A reappraisal of the value of carcinoembryonic antigen in the management of patients with various neoplasms

Journal of British Surgery, 1979
Summary Eight hundred and eight patients with histologically proved malignant disease had carcinoembryonic antigen (CEA) estimations performed at the time of tissue diagnosis. An elevated level was found in 384 of 518 patients with gastrointestinal neoplasms (74 per cent) and in 162 of 290 patients with other neoplasms (56 per cent).
Colin R. Mackie, David B. Skinner, M J Cooper, A. R. Moossa   +3 more
openaire   +3 more sources

Rearrangements of T-cell antigen receptor delta chain gene in hematologic neoplasms [PDF]

Blood, 1989
Rearrangements of the T-cell antigen receptor (TCR) delta chain gene were studied in primary neoplastic cells from 137 patients with leukemia or lymphoma. TCR delta gene rearrangements or deletions were observed in all 50 T-cell neoplasms: 5 of 8 CD3- T-cell neoplasms showed rearrangements, whereas biallelic deletion of TCR delta gene was the most ...
Fumio Kawano, Toshio Hattori, Masao Matsuoka, Norio Asou, Kiyoshi Takatsuki   +4 more
openaire   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

PET/CT imaging for tumour response assessment to immunotherapy: current status and future directions

European Radiology Experimental, 2020
Recent immunotherapeutic approaches have evolved as powerful treatment options with high anti-tumour responses involving the patient’s own immune system. Passive immunotherapy applies agents that enhance existing anti-tumour responses, such as antibodies
Marcus Unterrainer, Michael Ruzicka, Matthias P. Fabritius, Lena M. Mittlmeier, Michael Winkelmann, Johannes Rübenthaler, Matthias Brendel, Marion Subklewe, Michael von Bergwelt-Baildon, Jens Ricke, Wolfgang G. Kunz, Clemens C. Cyran   +11 more
doaj   +1 more source

Malignant lymphomas in transplantation patients: a review of the world experience. [PDF]

, 1970
Malignant lymphomas developed in 9 renal homograft recipients treated at widely separated transplantation centers. The development of these tumors appears to be an indirect complication of organ transplantation and/or the measures taken to prevent ...
Penn, I, Starzl, TE
core