Results 91 to 100 of about 19,573 (217)

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose, Irit Dahan, Alexander Upcher, Ran Zalk, Iris Grossman‐Haham   +4 more
wiley   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho, Perrine Henry, Mica Taylor, Catherine Davidson, María Lázaro Muñoz, Efa Llewellyn, Maša Vilfan, Paola Cazzini, Linda Morrison, Kelly Blacklock, Danièlle Gunn‐Moore   +10 more
wiley   +1 more source

A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology.

, 2007
Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8+ cytotoxic T lymphocytes.
Pellé, Roger, de Villiers, EP, Pierre van der Bruggen, Bruggen, P. van der, Shah, Tushaar, Glew, E.J., Mwangi, Duncan M, Shah, Trushar, Taracha, Evans L N, Honda, Y, Honda, Yoshikazu, Richard Bishop, Evans LN Taracha, Nene, Vishvanath, Villiers, Etienne P. de, Honda, Y., Mwangi, DM, Taracha, E.L.N., Bishop, R, Roger Pellé, Glew, E Jane, Glew, EJ, Shah, T, Nene, Vishvanath M., Etienne P de Villiers, Graham, SP, Bishop, Richard P., Yoshikazu Honda, Trushar Shah, Mwangi, David Miano, Nene, V, Simon P Graham, van der Bruggen, Pierre, Vishvanath Nene, Taracha, EL, van der Bruggen, P, Pellé, R, Duncan M Mwangi, Bishop, Richard, E Jane Glew, de Villiers, Etienne P, Graham, Simon P, Graham, S.P.   +42 more
core   +1 more source

Chloroplast-Derived Anthrax And Other Vaccine Antigens: Their Immunogenic And Immunoprotective Properties

, 2006
Transgenic plants offer many advantages, including low cost of production (by elimination of fermenters), storage and transportation, heat stability, absence of human pathogens, protection of antigens in the stomach through bioencapsulation (when ...
Kamarajugadda, Sushama, Daniell, Henry
core   +2 more sources

Seroprevalence of Neospora caninum in Camelids of the New and Old World: A Global Systematic Review and Meta‐Analysis

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Based on the present systematic review and meta‑analysis, the pooled prevalence of N. caninum in camelids was 10% (95% CI: 7%–12%) with significant heterogeneity (I2 = 93.75%, p < 0.0001). The highest rate was detected in Old World camelids, 14% (95% CI: 10%–19%), indicating that this group is more susceptible to N. caninum exposure.
Nashmin Mohemmi, Seyed Ahmad Karamati, Ronak Miladi, Mohammad Taghi Khodayari, Helia Bashiri, Reza Faraji, Shahab Falahi, Somayeh Jalilian, Arezoo Bozorgomid, Yazdan Hamzavi   +9 more
wiley   +1 more source

The immunogenic properties of protozoan glycosylphosphatidylinositols in the mosquito Anopheles gambiae

, 2009
In contrast to humans, mosquitoes do not have an adaptive immune response to deal with pathogens, and therefore must rely on their innate immune system to deal with invaders.
Arrighi, Romanico B G, Schwarz, Ralph T, Debierre-Grockiego, Françoise, Faye, Ingrid,   +3 more
core   +1 more source

Transient transfection of Cryptosporidium parvum using green fluorescent protein (GFP) as a marker

, 2009
Cryptosporidium parvum is a protozoan parasite that infects a variety of mammals. The parasite has been shown to harbor a dsRNA virus (CPV) and in the present study, we have developed a CPV transient transfection system for this parasite by using green ...
Yu, X., Li, W., Li, J., Zhang, N., Liang, X., Zhang, X., Gong, P., Ma, G., Ryan, U.M.   +8 more
core  

Surface antigens of Toxoplasma gondii: variations on a theme.

, 2001
Toxoplasma gondii is an obligate intracellular protozoan parasite with an exceptionally broad host range. Recently, it has become apparent that the number of surface antigens (SAGs) it expresses may rival the number of genera it can infect. Most of these
Lekutis, C, Ferguson, DJ, Grigg, ME, Camps, M, Boothroyd, JC   +4 more
core   +1 more source

Recombinant proteins as promising antigens applied to the immunodiagnosis of Chagas disease: a scoping review

Frontiers in Microbiology
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is an important public health problem, occurring mainly in Latin America. The disease has a major social and economical effect, negatively impacting the life of the infected individuals, and
Carlos Ananias Aparecido Resende, Anna Júlia Ribeiro, Isadora Braga Gandra, Kamila Alves Silva, Lucas da Silva Lopes, Isabelle Caroline dos Santos Barcelos, Carolina Alves Petit Couto, Mariana Teixeira de Faria, Sabrina Paula Pereira, Sandra Rodrigues Xavier, Juliana Martins Machado, Mariana Campos da Paz, Ana Thereza Chaves, Eduardo Antônio Ferraz Coelho, Rodolfo Cordeiro Giunchetti, Miguel Angel Chávez-Fumagalli, Walderez Ornelas Dutra, Ana Alice Maia Gonçalves, Alexsandro Sobreira Galdino   +18 more
doaj   +1 more source

A major genetic locus in Trypanosoma brucei is a determinant of host pathology [PDF]

, 2009
The progression and variation of pathology during infections can be due to components from both host or pathogen, and/or the interaction between them. The influence of host genetic variation on disease pathology during infections with trypanosomes has ...
C. Michael R. Turner, Andy Tait, Tait Andy, Liam J Morrison, McLellan Sarah, C Michael R Turner, Annette MacLeod, Liam J. Morrison, Turner, C.M.R., Sweeney Lindsay, MacLeod Annette, Lindsay Sweeney, MacLeod, A., McLellan, S., MacLeod, Annette, Tait, Andy, Morrison, L.J., McLellan, Sarah, Turner, C Michael R, Sweeney, Lindsay, Morrison Liam J., Sweeney, L., Turner C. Michael R., Morrison, Liam J; id_orcid, Tait, A., Sarah McLellan   +25 more
core   +1 more source