Results 81 to 90 of about 31,670 (226)

Genome-wide screening and identification of new Trypanosoma cruzi antigens with potential application for chronic Chagas disease diagnosis.

open access: yesPLoS ONE, 2014
The protozoan Trypanosoma cruzi is the etiologic agent of Chagas disease, an infection that afflicts approximately 8 million people in Latin America. Diagnosis of chronic Chagas disease is currently based on serological tests because this condition is ...
João Luís Reis-Cunha   +12 more
doaj   +1 more source

Epidemic Preparedness—Leishmania tarentolae as an Easy-to-Handle Tool to Produce Antigens for Viral Diagnosis: Application to COVID-19

open access: yesFrontiers in Microbiology, 2021
To detect and prevent emerging epidemics, discovery platforms are urgently needed, for the rapid development of diagnostic assays. Molecular diagnostic tests for COVID-19 were developed shortly after the isolation of SARS-CoV-2.
Ilaria Varotto-Boccazzi   +19 more
doaj   +1 more source

Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro [PDF]

open access: yes, 2013
Parasite infections are largely dependent on interactions between pathogen and different host cell populations to guarantee a successful infectious process.
Alves, Maria Julia Manso   +2 more
core   +2 more sources

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose   +4 more
wiley   +1 more source

The Genesis of Malaria: The Origin of Mosquitoes and Their Protistan Cargo, Plasmodium falciparum [PDF]

open access: yes, 2013
Malaria is caused by the parasite belonging to the genus Plasmodium; however, creation biologists maintain this organism was not always parasitic. Plasmodium is probably a degenerate form of algae.
Gillen, Alan L., Sherwin, Frank
core   +1 more source

The importance of vertical transmission of Neospora sp. in naturally infected horses [PDF]

open access: yes, 2012
Neospora spp. is a intracellular protozoan phylogenetically closely related to Toxoplasma gondii and Sarcocystis neurona, and it can infect horses leading to the development of reproductive or neurological diseases.
Ana Maria Antonello   +31 more
core   +4 more sources

Successful Management of Septic Splenitis in an Abyssinian Cat

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho   +10 more
wiley   +1 more source

Leishmania tarentolae as a platform for the production of vaccines against viral pathogens

open access: yesnpj Vaccines
Infectious diseases remain a persistent public health problem and a leading cause of morbidity and mortality in both humans and animals. The most effective method of combating viral infections is the widespread use of prophylactic vaccinations, which are
Marta Zimna, Ewelina Krol
doaj   +1 more source

Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts

open access: yesParasites & Vectors, 2018
Background Toxoplasma gondii is an obligate intracellular protozoan parasite that causes congenital toxoplasmosis, as well as other serious clinical presentations in immune compromised humans.
Mert Döşkaya   +8 more
doaj   +1 more source

Comparative Transcriptomics of the Bovine Apicomplexan Parasite Theileria parva Developmental Stages Reveals Massive Gene Expression Variation and Potential Vaccine Antigens

open access: yesFrontiers in Veterinary Science, 2020
Theileria parva is a protozoan parasite that causes East Coast fever (ECF), an economically important disease of cattle in Africa. It is transmitted mainly by the tick Rhipicephalus appendiculatus.
Kodzo Atchou   +10 more
doaj   +1 more source

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