Results 101 to 110 of about 31,670 (226)

First detection of intestinal microsporidia in Northern Nigeria [PDF]

, 2005
Microsporidia are intracellular spore-forming protozoa that are increasingly being recognized as pathogens in humans. Faecal samples were taken from 2250 HIV/AIDS and 1050 HIV-negative patients from Kano and Makurdi in Northern Nigeria, and were ...
A B, Yako, D D, Duhlinska, G I, Anyanwu, I CJ, Omalu, P U, Inyama, V A, Pam   +5 more
core   +1 more source

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Visceral Leishmaniasis in Somalia: Diagnosis and Management of a Classic Case in a Resource‐Limited Endemic Setting

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Visceral Leishmaniasis (VL), a severe systemic neglected tropical disease (NTD) caused by Leishmania donovani complex protozoa, poses a significant public health threat, particularly in East Africa, where it is fatal if untreated. Somalia is known to be endemic, but the true burden and programmatic challenges are poorly documented due to long ...
Abdirahman Nuur Hussein, Abdirahman Omer Ali, Ridwan Zakariye Ahmed, Sihaam Mohamed Abdirahman, Ahmed Dek Abdiwahab   +4 more
wiley   +1 more source

Expression, characterisation and antigenicity of a truncated Hendra virus attachment protein expressed in the protozoan host Leishmania tarentolae

Journal of Virological Methods, 2016
Hendra virus (HeV) is an emerging zoonotic paramyxovirus within the genus Henipavirus that has caused severe morbidity and mortality in humans and horses in Australia since 1994. HeV infection of host cells is mediated by the membrane bound attachment (G) and fusion (F) glycoproteins, that are essential for receptor binding and fusion of viral and ...
Fischer, Kerstin, dos Reis, Vinicius Pinho, Finke, Stefan, Sauerhering, Lucie, Stroh, Eileen, Karger, Axel, Maisner, Andrea, Groschup, Martin H., Diederich, Sandra, Balkema-Buschmann, Anne   +9 more
openaire   +2 more sources

Recombinant anticoccidial vaccines - a cup half full? [PDF]

, 2017
Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The occurrence of coccidiosis is currently controlled through a combination of good husbandry, chemoprophylaxis and/or live parasite vaccination; however, scalable ...
Ahmad, Arnott, Awad, Bafundo, Blake, Blake, Blake, Brothers, Brown, Chapman, Chapman, Chapman, Chapman, Chapman, Chapman, Chapman, Chapman, Chen, Clark, Clark, Cornelissen, Cosentino, Crane, Dalloul, Damer P. Blake, Ding, Ding, Djemai, Du, Eckford, Fiona M. Tomley, Fischbach, Fluit, Gedik, Gowen, Hedhli, Hoan, Huang, Iván Pastor-Fernández, Jahn, Jang, Jang, Jenkins, Jenkins, Jenkins, Jiang, Joyner, Karlsson, Keestra, Klotz, Koblansky, Konjufca, Kundu, Kvicerova, Labbe, Lai, Lassen, Lee, Li, Li, Lillehoj, Liu, Long, Marugan-Hernandez, Matthew J. Nolan, McDonald, McDonald, Min, Naciri, Nolan, Peek, Peek, Plattner, Pogonka, Reid, Ruff, Rugarabamu, Salazar Gonzalez, Sathish, Schaap, Shah, Sharman, Shen, Shirley, Shirley, Smith, Song, Song, Song, Song, Song, Song, Song, Subramanian, Sun, Takala, Tang, Tomley, Tomley, Tomley, Vermeulen, Vrba, Wallach, Wang, Wang, Williams, Williams, Williams, Williams, Williams, Witcombe, Wu, Xu, Xu, Yin, Yin, Yun, Zhang, Zhang, Zimmermann   +119 more
core   +2 more sources

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source

Highly syntenic and yet divergent: a tale of two Theilerias [PDF]

, 2009
The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their
Bishop, R., Chaussepied, M., de Villiers, E.P., Langsley, G., Shiels, B., Skilton, R., Sunter, J., Tait, A., Weir, W.   +8 more
core   +1 more source

The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub‐Saharan Africa: A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aim Despite its role in healthcare delivery and accessibility, the potential of bioinformatics to transform disease diagnosis in SSA remains unknown. This narrative review aims to assess the current status of bioinformatics initiatives in SSA and evaluate the role of bioinformatics in transforming diagnosis of major diseases in ...
Wilfred Ofosu, Fleischer C. N. Kotey, Alex Odoom, Onyansaniba K. Ntim, Eric S. Donkor   +4 more
wiley   +1 more source

Recombinant proteins as promising antigens applied to the immunodiagnosis of Chagas disease: a scoping review

Frontiers in Microbiology
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is an important public health problem, occurring mainly in Latin America. The disease has a major social and economical effect, negatively impacting the life of the infected individuals, and
Carlos Ananias Aparecido Resende, Anna Júlia Ribeiro, Isadora Braga Gandra, Kamila Alves Silva, Lucas da Silva Lopes, Isabelle Caroline dos Santos Barcelos, Carolina Alves Petit Couto, Mariana Teixeira de Faria, Sabrina Paula Pereira, Sandra Rodrigues Xavier, Juliana Martins Machado, Mariana Campos da Paz, Ana Thereza Chaves, Eduardo Antônio Ferraz Coelho, Rodolfo Cordeiro Giunchetti, Miguel Angel Chávez-Fumagalli, Walderez Ornelas Dutra, Ana Alice Maia Gonçalves, Alexsandro Sobreira Galdino   +18 more
doaj   +1 more source

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]

Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio, Antoniou, Maria, Begoña Ruiz-Argüello, Maria, Blackwell, Jenefer M., Carson, Connor, Christodoulou, Vasiliki, Courtenay, Orin, Messaritakis, Ippokratis   +7 more
core   +1 more source