Expression and clinical significance of peripheral blood NK cell surface co-signaling molecules in active pulmonary tuberculosis patients. [PDF]
Tong J +8 more
europepmc +1 more source
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Simultaneous and sensitive detection of <i>Mycobacterium tuberculosis</i> and SARS-CoV-2 antigens employing an electrochemical impedance spectroscopy aptasensor. [PDF]
Zhumabekova Z +3 more
europepmc +1 more source
A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng +8 more
wiley +1 more source
Polymeric particle-based antigen delivery system: From immunological engineering to clinical translation. [PDF]
Shi Y +9 more
europepmc +1 more source
The pyrogallol‐conjugated carboxymethylcellulose (CMC‐PG) hydrogel is applicated as a filler for the treatment of presbylaryngis, a vocal fold atrophy. CMC‐PG provides a bulking effect to the vocal folds. CMC‐PG is readily injectable and tissue adhesive, enabling sustained release of growth factor over long period.
Jihoon Jeon +7 more
wiley +1 more source
Isohemagglutinins exhibit synergistic polyreactivity toward Streptococcus pneumoniae surface antigens: implications for broad-spectrum reactivity of human antibodies. [PDF]
Bernth Jensen JM +7 more
europepmc +1 more source
A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan +3 more
wiley +1 more source
Probiotics lead to a new frontier in tumor fighting: tumor vaccines based on probiotics. [PDF]
Ma T, Qi L, Zhou Z, Shen J.
europepmc +1 more source
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee +9 more
wiley +1 more source

