Results 151 to 160 of about 370,392 (197)

Pox-AbDab: the orthopoxvirus antibody database. [PDF]

Front Immunol
Capel HL, Wang EJD, Williams BH, Deane CM, Raybould MIJ.   +4 more
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Effects of Dietary Sodium Modulation on Circulating Extracellular Vesicles. [PDF]

Hypertension
Burrello J, Buffolo F, Honzel B, Tsai LC, Tetti M, Burrello A, Di Silvestre D, Mauri P, Capuzzo V, Bruno S, Barile L, Mulatero P, Vaidya A, Monticone S.   +13 more
europepmc   +1 more source

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

Emerging strategies for monkeypox: antigen and antibody applications in diagnostics, vaccines, and treatments. [PDF]

Mil Med Res
Wang W, Li JX, Long SQ, Liu ZN, Li XP, Peng ZH, Zheng JD, Liao YH.   +7 more
europepmc   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Profiling Human Papillomavirus Lineage-Specific Capsid Antigenicity With Geographically Diverse Natural Infection Antibodies. [PDF]

J Infect Dis
Panwar K, Yokoya K, Gomes S, Tenet V, Schussler J, Herrero R, Mirabello L, Schiller JT, Sierra MS, Clifford GM, Beddows S.   +10 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Comparative humoral profiles in mpox cases, survivors, and vaccinated individuals reveal correlates of protection against MPXV. [PDF]

Cell Rep Med
Wang Y, Zhang L, Zhou L, Chen J, Zhang Z, Wu T, Wei P, Zhu A, Cai R, Zhang J, Lin Z, Chen C, Zhang Y, Zhong Q, Sun J, Shi Y, Zhao J, Dai J, Qin P, Zhao J.   +19 more
europepmc   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source