Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd+8 more
wiley +1 more source
Anti-endothelial cell antibodies in pathogenesis of vasculitis. [PDF]
Zhang T+4 more
europepmc +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao+7 more
wiley +1 more source
Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse. [PDF]
McArthur HCW+3 more
europepmc +1 more source
Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande+2 more
wiley +1 more source
Glycoengineering of the hepatitis C virus E2 glycoprotein improves biochemical properties and enhances immunogenicity. [PDF]
Kulakova L+20 more
europepmc +1 more source
This study addresses bacterial biofilm resistance by developing mesoporous Fe3O4 nanoparticles loaded with photosensitizer IR‐820, enabling combined antimicrobial photodynamic therapyand magnetic hyperthermia therapy. The system achieves magnetic targeting, heat‐triggered drug release under alternating magnetic fields, and near‐infrared‐induced ROS ...
Yuange Li+8 more
wiley +1 more source
An mRNA vaccine against monkeypox virus inhibits infection by co-activation of humoral and cellular immune responses. [PDF]
Tai W+19 more
europepmc +1 more source
This study presents the development of large‐scale (15 cm2) cartilage constructs with anisotropic mechanical properties using melt electrowritten (MEW) microfiber reinforced cell‐laden gelatin methacryloyl (gelMA). These constructs mimic the mechanical behavior of native cartilage, providing a suitable environment for Articular Cartilage ...
Lennard Spauwen+5 more
wiley +1 more source
Targeted Drug Delivery to the Spleen and Its Implications for the Prevention and Treatment of Cancer. [PDF]
Khalil IA, Faheem A, El-Tanani M.
europepmc +1 more source