Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle [PDF]
Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp.
Blake, D P +4 more
core +1 more source
Persistence of Antigen on the Surface of Macrophages [PDF]
MOUSE peritoneal macrophages can take up and catabolize two different haemocyanins1,2. Although in tissue culture experiments most of these materials were broken down in a few hours after uptake, haemocyanin nevertheless elicited the formation of specific antibodies when the macrophages were transferred to syngeneic hosts, and the haemocyanin bound to ...
Unanue, E R, Cerottini, J, Bedford, M
openaire +2 more sources
New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J. +3 more
core +2 more sources
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]
Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core +4 more sources
Helping tumour antigens to the surface [PDF]
Using high-resolution proteomics to analyse clinical samples from patients with advanced melanoma, Harel et al. show that the metabolic state of melanoma is associated with changes in antigen presentation-related proteins and thereby with response to immunotherapies.
openaire +2 more sources
Role of the pathologist in the diagnosis of autoimmune encephalitis
Autoimmune encephalitis is a group of non-infectious immune-mediated inflammatory disorders manifesting with epilepsy and encephalitis syndromes that are associated with autoantibodies in the serum and/or cerebrospinal fluid (CSF).
Shilpa Rao +2 more
doaj +1 more source
Detection of microbial surface antigens that bind Lewisa antigen [PDF]
There is evidence that the Lewis(a) blood group antigen is one of the receptors for a number of potentially pathogenic microorganisms. To determine how widely distributed the microbial adhesins are that bind this antigen, anti-idiotypic antibodies produced against monoclonal anti-Lewis(a) were used in coagglutination assays to screen a variety of ...
S D, Essery +6 more
openaire +2 more sources
A surface antigen influenza vaccine: 2. Pyrogenicity and antigenicity [PDF]
SummaryConventional influenza vaccine containing whole virus particles purified on a zonal centrifuge is pyrogenic and can cause systemic and local adverse side effects. An improved vaccine was therefore prepared which contained only the surface antigens of the virus adsorbed to aluminium hydroxide.
M I, Brady, I G, Furminger
openaire +2 more sources
Background The efficacy of highly active antiretroviral therapy (HAART) determined by simultaneous monitoring over 100 cell-surface antigens overtime has not been attempted.
Wang Bin +5 more
doaj +1 more source
Production and characterization of chimeric monoclonal antibodies against Burkholderia pseudomallei and B. mallei using the DHFR expression system. [PDF]
Burkholderia pseudomallei (BP) and B. mallei (BM) are closely related gram-negative, facultative anaerobic bacteria which cause life-threatening melioidosis in human and glanders in horse, respectively.
Hyung-Yong Kim +4 more
doaj +1 more source

