Pooled protein immunization for identification of cell surface antigens in Streptococcus sanguinis. [PDF]
PLoS ONE, 2010 Available bacterial genomes provide opportunities for screening vaccines by reverse vaccinology. Efficient identification of surface antigens is required to reduce time and animal cost in this technology.
Xiuchun Ge +4 more
doaj +1 more source
Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]
, 1979 Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Barz, D. +3 more
core +1 more source
Surface antigens ofToxoplasma gondii
Parasitology, 1988 SUMMARYMonoclonal antibodies reacting with pellicular antigens ofToxoplasma gondiitachyzoites have been selected among hybridomas produced against this organism by immunofluorescence assay. These antigens have been further characterized by immunofluorescence on living zoites, Western immunoblotting and immunoprecipitation of lactoperoxidase surface ...
Jean-François Dubremetz +3 more
openaire +3 more sources
Recombinant subunit vaccines against Neospora caninum [PDF]
, 2007 The intracellular protozoan parasite Neospora caninum is an important cause of bovine abortion and congenital infection in many countries. Currently there is no effective control method available, and development of a vaccine has been suggested as a ...
Pinitkiatisakul, Sunan
core
Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]
, 2008 Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Aguero-Rosenfeld ME +57 more
core +1 more source
Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex
Emerging Infectious Diseases, 1997 Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
doaj +1 more source
Protective vaccination in the horse against _Streptococcus equi_ with recombinant antigens [PDF]
, 2009 _Streptococcus equi_ subspecies _equi_ (_S. equi_) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, more commonly known as Strangles.
Andrew Waller +6 more
core +1 more source
Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]
, 2013 Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E. +4 more
core +2 more sources
Antigenicity of hepatitis B surface antigen proteins reconstituted with phospholipids
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1995 Hepatitis B surface antigen (HBsAg) has been reconstituted with different phospholipid classes. All epitopes defined by a panel of monoclonal antibodies which recognize both group- and subtype-specific antigenic determinants showed specificity for acidic phospholipids.
Darrell L. Peterson +3 more
openaire +3 more sources
Conjugation of an scFab domain to the oligomeric HIV envelope protein for use in immune targeting.
PLoS ONE, 2019 A promising strategy for the enhancement of vaccine-mediated immune responses is by directly targeting protein antigens to immune cells. Targeting of antigens to the dendritic cell (DC) molecule Clec9A has been shown to enhance antibody affinity and ...
Hannah A D King +7 more
doaj +1 more source