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Uses of Biosensors in the Study of Viral Antigens

Immunological Investigations, 1997
The introduction in 1990 of a new biosensor technology based on surface plasmon resonance has greatly simplified the measurement of binding interactions in biology. This new technology known as biomolecular interaction analysis makes it possible to visualize the binding process as a function of time by following the increase in refractive index that ...
van Regenmortel, M. H.   +5 more
openaire   +4 more sources

Australia Antigen and Acute Viral Hepatitis

Annals of Internal Medicine, 1969
Abstract Australia antigen (Au(1)) was found in the sera of 20% of 125 patients with acute viral hepatitis.
Alton I. Sutnick   +2 more
openaire   +3 more sources

Antigen Detection in the Diagnosis of Viral Infections

Scandinavian Journal of Infectious Diseases, 1988
The value of viral antigen detection from nasopharyngeal secretion (NPS) by enzyme immunoassay (EIA) in everyday clinical practice was evaluated in 570 children hospitalized because of infections. NPS-EIA gave a positive result in 32% of all cases.
Matti Uhari, Hanna Tuokko, Jukka Hietala
openaire   +3 more sources

Delivery of Antigens by Viral Vectors for Vaccination

Therapeutic Delivery, 2010
Viral vectors have been developed as vaccine platforms for a number of pathogens and tumors. In particular, adenovirus (Ad)-based vectors expressing genes coding for pathogen or tumor antigens have proven efficacious to induce protective immunity. Major challenges in the use of Ad vectors are the high prevalence of anti-Ad immunity and the recent ...
Anja Krause, Stefan Worgall
openaire   +2 more sources

Antibody Response to Viral Antigens

1973
Publisher Summary This chapter focuses on humoral antibody response. It describes the general nature of viral antigens, what is being determined by seriological procedures applied to virus systems, the appraisal of such data for diagnostic and vaccine evaluation purposes, and the nature of the antibody response and some potential implications to ...
openaire   +3 more sources

Relationship of hepatitis A antigen to viral hepatitis

The American Journal of the Medical Sciences, 1975
Progress in research on hepatitis type A has begun to accelerate because of the recent discovery of an antigen associated specifically with hepatitis type A infection and the development of tests for antibody to the antigen. Hepatitis A antigen is associated with 27 nm virus-like particles found in the liver and stool of animals experimentally infected
Jules L. Dienstag   +3 more
openaire   +3 more sources

Australia Antigen, an Antigen Associated with Viral Hepatitis

1972
The long history of epidemic jaundice and the outbreaks of hepatitis which followed the introduction of large-scale parenteral therapy in venereal disease clinics, diabetic clinics, tuberculosis sanatoria and immunization centres, and hepatitis associated with the transfusion of blood and blood products, have recently been reviewed (Zuckerman, 1970a ...
openaire   +3 more sources

Immunolabeling of Viral Antigens in Infected Cells

1991
Since its introduction in 1971 [2], labeling of antigens with gold particles to facilitate the detection of these antigens in thin sections of infected tissue by electron microscopy has proven to be a powerful technique. Also in plant pathology and especially in plant virology [4], this detection system has been applied frequently, enabling studies ...
van Lent, J.W.M., Verduin, B.J.M.
openaire   +3 more sources

Viral Hepatitis and the Australia-SH Antigen

Nature, 1969
Recent work has shed new light on an old disease. Australia antigen seems to be associated with small spherical particles which could be the agents of hepatitis.
openaire   +3 more sources

Detection of Hepatitis a Viral Antigen by Radioimmunoassay

The Journal of Immunology, 1975
Abstract In 1973, Feinstone et al. (1), with the technique of immune electron microscopy (IEM)2 (2), detected virus particles in acute-phase stool suspensions obtained from patients with type A hepatitis. This technique was useful in further characterizing hepatitis A virus, but required the expertise of a skilled electron microscopist ...
F B, Hollinger   +4 more
openaire   +2 more sources

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